Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

20-110 Src Manganese/ATP Cocktail

Src Manganese/ATP Cocktail MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Key Applications: Kinase Assay
20-110
1 mL  
Purchase on Sigma-Aldrich

概述

Replacement Information

重要规格表

Key Applications
KA
Description
Catalogue Number20-110
Brand Family Upstate
Trade Name
  • Upstate
DescriptionSrc Manganese/ATP Cocktail
References
Product Information
Presentation20mM MOPS, pH 7.2, 25mM β-glycerol phosphate, 5mM EGTA, 1mM sodium orthovanadate, 1mM dithiothreitol
Quality LevelMQ100
Applications
Key Applications
  • Kinase Assay
Application NotesFor use in kinase assays.
Biological Information
Entrez Gene Number
Entrez Gene SummaryThis gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene.
Gene Symbol
  • SRC
  • ASV
  • c-src
  • p60-Src
  • SRC1
  • c-SRC
  • pp60c-src
UniProt Number
UniProt SummarySIZE: 536 amino acids; 59835 Da
SUBUNIT: Interacts with DDEF1/ASAP1 via its SH3 domain. Interacts with CCPG1 (By similarity). Interacts with CDCP1, PELP1, TGFB1I1 and TOM1L2.
PTM: Phosphorylated on Tyr-530 by c-Src kinase (CSK). The phosphorylated form is termed pp60c-src. The phosphorylated tail interacts with the SH2 domain thereby repressing kinase activity.
SIMILARITY: SwissProt: P12931 ## Belongs to the protein kinase superfamily. Tyr protein kinase family. SRC subfamily. & Contains 1 protein kinase domain. & Contains 1 SH2 domain. & Contains 1 SH3 domain.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage Conditions1 year at -20°C
Packaging Information
Material Size1 mL
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
产品目录编号 GTIN
20-110 04053252736452

Documentation

Src Manganese/ATP Cocktail MSDS

职位

物料安全数据表 (MSDS) 

Src Manganese/ATP Cocktail 分析证书

标题批号
Src Manganese/ATP Cocktail 2891469
Src Manganese/ATP Cocktail - 2140558 2140558
Src Manganese/ATP Cocktail - 2299963 2299963
Src Manganese/ATP Cocktail - 2383486 2383486
Src Manganese/ATP Cocktail - 2438253 2438253
Src Manganese/ATP Cocktail - 3889671 3889671
Src Manganese/ATP Cocktail - Any-lot Any-lot
Src Manganese/ATP Cocktail - DAM1598765 DAM1598765
Src Manganese/ATP Cocktail - JBC1395498 JBC1395498
Src Manganese/ATP Cocktail -2514497 2514497
Show more