579052 Sigma-AldrichTAPI-2 - CAS 187034-31-7 - Calbiochem
TAPI-2, CAS 187034-31-7, is a hydroxamate-based inhibitor of MMPs and TACE. Inhibits the activation-induced shedding of L-selectin from neutrophils, eosinophils, and lymphocytes.
More>> TAPI-2, CAS 187034-31-7, is a hydroxamate-based inhibitor of MMPs and TACE. Inhibits the activation-induced shedding of L-selectin from neutrophils, eosinophils, and lymphocytes. Less<<TAPI-2 - CAS 187034-31-7 - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-t-butyl-alanyl-L-alanine, 2-aminoethyl Amide, TNF-α Protease Inhibitor-2
Recommended Products
概述
| Replacement Information |
|---|
重要规格表
| CAS # | Empirical Formula |
|---|---|
| 187034-31-7 | C₁₉H₃₇N₅O₅ |
Products
| 产品目录编号 | 包装 | 数量 / 包装 | |
|---|---|---|---|
| 579052-1MGCN | 塑胶安瓿;塑胶针药瓶 | 1 mg |
| Description | |
|---|---|
| Overview | A hydroxamate-based inhibitor of MMPs and TACE. Inhibits the activation-induced shedding of L-selectin from neutrophils, eosinophils, and lymphocytes, as well as phenylarsine oxide (PAO)-induced shedding in neutrophils. Also acts as a weak inhibitor of angiotensin converting enzyme (IC50 = 18 µM). Also available as a 10 mM solution in H2O (Cat. No. 509612). |
| Catalogue Number | 579052 |
| Brand Family | Calbiochem® |
| Synonyms | N-(R)-[2-(Hydroxyaminocarbonyl)methyl]-4-methylpentanoyl-L-t-butyl-alanyl-L-alanine, 2-aminoethyl Amide, TNF-α Protease Inhibitor-2 |
| Product Information | |
|---|---|
| CAS number | 187034-31-7 |
| ATP Competitive | N |
| Declaration | Manufactured exclusively by Peptides International, Louisville, Kentucky, USA. |
| Form | White solid |
| Hill Formula | C₁₉H₃₇N₅O₅ |
| Chemical formula | C₁₉H₃₇N₅O₅ |
| Hygroscopic | Hygroscopic |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
|---|
| Biological Information | |
|---|---|
| Primary Target | MMPs |
| Primary Target IC<sub>50</sub> | 18 µM against angiotensin converting enzyme |
| Purity | ≥97% by HPLC |
| Physicochemical Information | |
|---|---|
| Cell permeable | N |
| Dimensions |
|---|
| Materials Information |
|---|
| Toxicological Information |
|---|
| Safety Information according to GHS |
|---|
| Safety Information |
|---|
| Product Usage Statements |
|---|
| Packaging Information | |
|---|---|
| Packaged under inert gas | Packaged under inert gas |
| Transport Information |
|---|
| Supplemental Information |
|---|
| Specifications |
|---|
| Global Trade Item Number | |
|---|---|
| 产品目录编号 | GTIN |
| 579052-1MGCN | 04055977265378 |
Documentation
TAPI-2 - CAS 187034-31-7 - Calbiochem MSDS
| 职位 |
|---|
TAPI-2 - CAS 187034-31-7 - Calbiochem 分析证书
| 标题 | 批号 |
|---|---|
| 579052 |
参考
| 参考信息概述 |
|---|
| Bennett, T.A., et al. 2000. J. Immunol. 164, 4120. Fiorucci, S., et al. 1998. Aliment. Pharmacol. Ther. 12, 1139. Hooper, N.M., et al. 1997. Biochem. J. 321, 265. Parvathy, S., et al. 1997. Biochem. J. 327, 37. Arribas, J., et al. 1996. J. Biol. Chem. 271, 11376. |