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clarisolve

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Product Announcement | Clarisolve® mPAA Flocculation Polymer | Merck
The Clarisolve® mPAA polymer is a stimulus-responsive flocculation polymer designed specifically to enable a simpler clarification of high density cell culture monoclonal antibody (mAb) processes, and provides an alternative to centrifugation for these challenging bioreactor harvests when used in combination with Clarisolve® depth filters.
Clarisolve® Depth Filters & pDADMAC Flocculation Polymer | Merck
Information on pDADMAC (diallyldimethyl-ammonium chloride) and mPAA Polycationic polymer modified poly (allyl amine) flocculation polymer, pre-treatment solutions for clarification of pre-treated feed streams.
Clarisolve® Depth Filters | Downstream Processing | Biopharmaceutical Manufacturing | Merck
Clarisolve® Depth Filters, provides fastest and most efficient way to clarify high-density pre-treated feed streams.
Clarisolve® Depth Filters | Harvest | Biopharmaceutical Manufacturing | Merck
Clarisolve® Depth Filters, Provides fastest and most efficient way to clarify high-density pre-treated feed streams.
Clarification Primer | Clarification Learning Center | Biopharmaceutical Manufacturing | Merck
Clarification of mammalian cell culture involves multiple steps and, typically, a systematic combination of unit operations which can include centrifugation, tangential flow filtration, depth filtration, and sterile filtration.
Optimization and Process Simulation | Clarification Learning Center | Biopharmaceutical Manufacturing | Merck
At the process optimization stage, begin work on confirmatory sizing trials (pilot testing). Further confirmation of your initial sizing studies is important since the cell culture fluid has most likely been through optimization
Scale-up and Design Finalization | Clarification Learning Center | Biopharmaceutical Manufacturing | Merck
The goals of scale-up are to create reproducible product yield, contaminant removal, quality, and purity. Design finalization is your next critical challenge.
Full-scale Processing | Clarification Learning Center | Biopharmaceutical Manufacturing | Merck
Once the process of scale-up is completed and commercial production has started, what can help you to ensure smooth operation in the years ahead? Find services and expertise can help you meet this goal.
Press Release: Merck Introduces Novel Clarisolve® Depth Filters that Deliver Unmatched Speed and Efficiency for Single-Stage Clarification of Pretreated Feed Streams
Merck, today introduced the Clarisolve® depth filter for single-stage clarification of pretreated feed streams.
Available Depth Filters | Merck
To meet your downstream processing needs, lead times for Millistak+® HC, Millistak+® HC Pro and Clarisolve® Depth filters for primary and secondary clarification have been reduced. Products are in stock, and we are back to business as usual.