Custom Premix Selecting "Custom Premix" option means that all of the beads you have chosen will be premixed in manufacturing before the kit is sent to you.
Learn about the environmental factors that can hinder DNA repair. There are many evidence linking genomic and epigenomic changes to disorders involving accelerated aging. Evidence points to general physiological stress and disrupted circadian. It is also possible that decreased DNA repair is also a symptom, not a cause, of aging. To investigate this possibility, researchers will need to examine changes in transcriptional regulators of repair genes, such as ncRNAs, hormones, and other chromatin modulators.
Oxidative stress is a cellular disorder caused by an excess of free radicals resulting from increased oxidant levels, decreased anti-oxidant amounts, or failure to repair damage induced by reactive oxygen species (ROS).
Organisms depend on multiple nutrient sensing pathways to make sure that the cells and tissue obtain just the right amount of necessary nutrients. Metabolic activities can put stress on our cells. Too much activity, and changes in nutrient availability and composition cause cells to age faster.
LC3-II enrichment Kit (Western Blot) enables quantification of autophagosome density by utilizing a permeabilization procedure that reveals quantities of LC3-II, without interference from LC3-I, by Western blotting analysis.
Caspase detection antibodies and assays are used to help detect and study caspase activation in Apoptotic cells via immunoprecipitation and immunoblotting techniques.
mPAGE™ precast polyacrylamide gels provide a cost-effective solution for high-resolution protein separation via polyacrylamide gel electrophoresis (PAGE). Compatible with most standard electrophoresis tanks, mPAGE™ precast gels for electrophoresis offer an increased sample well volume and a reduced run time.