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Merck

ARHGEF6

Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

Sinónimos:
COOL2, Cool-2, MRX46, PIXA, alpha-PIX, alphaPIX
Especie:
ID UniProtKB:
ID del gen:
  • Human(9459) Summary: Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein belongs to a family of cytoplasmic proteins that activate the Ras-like family of Rho proteins by exchanging bound GDP for GTP. It may form a complex with G proteins and stimulate Rho-dependent signals. This protein is activated by PI3-kinase. Mutations in this gene can cause X-chromosomal non-specific mental retardation. [provided by RefSeq, Jul 2008]
  • Mouse(73341) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Rat(363509) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Domestic Rabbit(100358647) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • chicken(422247) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • dog(610290) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • domestic cat(101099030) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • domestic guinea pig(100719019) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • naked mole-rat(101700245) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • Horse(100056622) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • cow(533823) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
  • sheep(101104043) Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6

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Antibodies

Número de producto
Descripción
Reactividad de especies
Aplicación
Monoclonal Anti-ARHGEF6 antibody produced in mouse, clone 2E5, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human
Aplicación
ELISA
immunoprecipitation (IP)

proximity ligation assay

western blot
Anti-ARHGEF6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

western blot
Anti-ARHGEF6, from rabbit, purified by affinity chromatography,
Reactividad de especies
bovine, human, mouse, rat, rhesus macaque
Aplicación
immunocytochemistry
western blot
Anti-Arhgef6 Antibody Produced In Rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reactividad de especies
human
Aplicación
immunofluorescence
Monoclonal Anti-Rac antibody produced in mouse, clone 23A8, purified immunoglobulin, buffered aqueous solution,
Reactividad de especies
human, mouse, rat
Aplicación
immunohistochemistry
immunoprecipitation (IP)

western blot

esiRNA

Número de producto
Descripción
Especie
MISSION® esiRNA, targeting mouse Arhgef6,
Especie
mouse
MISSION® esiRNA, targeting human ARHGEF6,
Especie
human