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Merck

AB9884

Anti-Clathrin Light Chain Antibody

serum, Chemicon®

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

serum

antibody product type

primary antibodies

clone

polyclonal

species reactivity

rat, human

manufacturer/tradename

Chemicon®

technique(s)

western blot: suitable

NCBI accession no.

NM_001076677.1
NM_001833.2
NM_007096.2

UniProt accession no.

P09496
P09497

shipped in

wet ice

target post-translational modification

unmodified

Gene Information

human ... CLTA(1211)

Categorías relacionadas

General description

~35-40 kDa

Application

This Anti-Clathrin Light Chain Antibody is validated for use in WB for the detection of Clathrin Light Chain.
Western blot: 1:50,000-1:100,000 on rat brain extracts.

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Clathrin light chain a and b variants (CLC). By Western blot the antibody recognizes a doublet at ~35-40 kDa on rat brain extracts.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Clase de almacenamiento

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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Fan Fan et al.
Proceedings of the National Academy of Sciences of the United States of America, 118(32) (2021-08-08)
Pancreatic β cells operate with a high rate of membrane recycling for insulin secretion, yet endocytosis in these cells is not fully understood. We investigate this process in mature mouse β cells by genetically deleting dynamin GTPase, the membrane fission
Kazuki Obashi et al.
Nature communications, 14(1), 732-732 (2023-02-10)
Conformational changes in endocytic proteins are regulators of clathrin-mediated endocytosis. Three clathrin heavy chains associated with clathrin light chains (CLC) assemble into triskelia that link into a geometric lattice that curves to drive endocytosis. Structural changes in CLC have been
Yang Yang et al.
Developmental cell, 43(4), 507-521 (2017-11-22)
Assembly of the endocytic machinery is a constitutively active process that is important for the organization of the plasma membrane, signal transduction, and membrane trafficking. Existing research has focused on the stochastic nature of endocytosis. Here, we report the emergence
Stephanie A Zlatic et al.
Molecular biology of the cell, 24(15), 2378-2388 (2013-06-14)
A role for clathrin in AP-3-dependent vesicle biogenesis has been inferred from biochemical interactions and colocalization between this adaptor and clathrin. The functionality of these molecular associations, however, is controversial. We comprehensively explore the role of clathrin in AP-3-dependent vesicle
Marwin Groener et al.
Kidney360, 1(6), 480-490 (2020-04-16)
Clathrin-mediated endocytosis (CME) plays a fundamental role in podocyte health. Genetic ablation of genes implicated in CME has been shown to cause severe proteinuria and foot process effacement in mice. However, little is known about the cargo of clathrin-coated vesicles
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SKUGTIN
AB988404053252675201

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