114700 Activin A, Human, Recombinant, CHO Cells

114700
Cenu nelze zjistit
Minimum Quantity needs to be mulitiple of
S dokončenou objednávkou Další informace
Ušetřili jste ()
 
Vyžádat nacenění
Omezená dostupnostOmezená dostupnost
Na skladě 
Přerušeno
Dostupné omezené množství
Dostupnost bude potvrzena
    Remaining : Will advise
      Remaining : Will advise
      Bude poskytnuto
      Kontaktujte Zákaznický servis
      Contact Customer Service
      Zobrazit ceny a dostupnost

      Přehled

      Replacement Information

      Tabulka spec. kláve

      Purity
      ≥95% by SDS-PAGE

      Ceny a dostupnost

      Katalogové číslo DostupnostBalení ks/bal. Cena Množství
      114700-10UG
      Zjišťuji dostupnost...
      Omezená dostupnostOmezená dostupnost
      Na skladě 
      Přerušeno
      Dostupné omezené množství
      Dostupnost bude potvrzena
        Remaining : Will advise
          Remaining : Will advise
          Bude poskytnuto
          Kontaktujte Zákaznický servis
          Contact Customer Service

          Plastová ampulka 10 μg
          Zjišťuji cenu...
          Cenu nelze zjistit
          Minimum Quantity needs to be mulitiple of
          S dokončenou objednávkou Další informace
          Ušetřili jste ()
           
          Vyžádat nacenění
          Description
          OverviewRecombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular weight of 13 kDa. A member of the TGF-β superfamily that is involved in the negative regulation of B lineage lymphocytes. Shown to play an important role in the regulation of hormonogenesis, cellular homeostasis, and differentiation programs. Reported to inhibit endogenous production of IL-6.
          Catalogue Number114700
          Brand Family Calbiochem®
          References
          ReferencesZipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.
          Product Information
          FormLyophilized
          FormulationLyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
          Quality LevelMQ100
          Applications
          Biological Information
          Biological activityED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
          Purity≥95% by SDS-PAGE
          Physicochemical Information
          ContaminantsEndotoxin: ≤100 pg/µg Activin A
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage ≤ -70°C
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Activin A, Human, Recombinant, CHO Cells Certificates of Analysis

          TitleLot Number
          114700

          References

          Přehled odkazů
          Zipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision07-April-2008 RFH
          DescriptionRecombinant, human activin A (disulfide-linked homodimer of two 116-amino acid residue βA subunits) expressed in CHO cells. Mature βA-monomer lacks a potential N-linked glycosylation site and has a calculated molecular mass of 13 kDa. Activins are members of the TGF-β superfamily and have been shown to play an important role in the regulation of homonogenesis, cellular homeostasis, and differentiation programs.
          FormLyophilized
          FormulationLyophilized from sterile filtered 35% acetonitrile, 0.1% TFA, 50 µg BSA/µg Activin A.
          Purity≥95% by SDS-PAGE
          ContaminantsEndotoxin: ≤100 pg/µg Activin A
          Biological activityED₅₀ = 0.5-2.0 ng/ml as measured by its ability to induce hemoglobin expression in K562 cells
          SolubilityReconstitute to a concentration ≥10 µg/ml with sterile PBS containing ≥0.1% HSA or BSA.
          Storage ≤ -70°C
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 3 months at -70°C. Avoid freeze/thaw cycles of solutions.
          Toxicity Standard Handling
          ReferencesZipori, D., et al. 2001. J. Leukoc. Biol. 69, 867.
          Hedger, M.P., et al. 2000. Cytokine 12, 595.
          Woodruff, T.K. 1998. Biochem. Pharmacol. 55, 953.
          Ying, S.Y., et al. 1997. Proc. Soc. Exp. Biol. Med. 214, 114.
          Schwall, R.H., and Lei, C. 1991. Methods Enzymol. 198, 340.
          Mason, A., et al. 1986. Biochem. Biophys. Res. Commun. 135, 957.