176700 Angiostatin® Protein, Human
Recommended Products
Přehled
Replacement Information |
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Description | |
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Overview | This product has been discontinued. We are offering Angiostatin K1-3, Human, Recombinant, P. pastoris (Cat. No. 176708) as a possible alternative. Please read the alternative product documentation carefully and contact technical service if you need additional information. A proteolytic fragment of plasminogen constituting kringles 1 - 4. A specific inhibitor of endothelial cell proliferation and one of the most potent and specific natural inhibitors of angiogenesis and metastatic tumor growth. Human angiostatin significantly inhibits bFGF-induced endothelial cell proliferation and migration at concentrations ranging from 300 nM - 1.0 µM. |
Catalogue Number | 176700 |
Brand Family | Calbiochem® |
Applications |
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Biological Information | |
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Purity | ≥98% by SDS-PAGE (migrates as a doublet) |
Source | Prepared from fluid that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV. |
Physicochemical Information | |
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Contaminants | plasmin, plasminogen: none detected |
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Materials Information |
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Toxicological Information |
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Safety Information according to GHS | |
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RTECS | BW2140000 |
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Product Usage Statements |
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Packaging Information |
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Supplemental Information |
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Specifications |
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Global Trade Item Number | |
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Katalogové číslo | GTIN |
176700 | 0 |
Documentation
Angiostatin® Protein, Human Certificates of Analysis
Title | Lot Number |
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176700 |
References
Přehled odkazů |
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Cao, Y. 1999. Haematologica 84, 643. Sim, B.K., et al. 1997. Cancer Res. 57, 1329. Wu, Z., et al. 1997. Biochem. Biophys. Res. Commun. 236, 651. Cao, Y., et al. 1996. J. Biol. Chem. 271, 29461. O’Reilly, M.S., et al. 1994. Cell 79, 315. |