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171615 Anti-β-Amyloid Precursor-Like Protein 1, C-Terminal (643-653) Rabbit pAb

171615
  
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Přehled

Replacement Information

Tabulka spec. kláve

Host
Rb
Description
Overview

This product has been discontinued.



Please refer to our complete listings of amyloid precursor protein antibodies and amyloid precursor protein antibodies on millipore.com for possible alternatives.






Recognizes the APLP1 protein. Does not recognize APP or APLP2.
  • Antibody Target Gene Symbol: APLP1
  • Target Synonym: APLP, Aplp1 retired, RGD1561211
  • Entrez Gene Name: amyloid beta (A4) precursor-like protein 1
  • Hu Entrez ID: 333
  • Mu Entrez ID: 11803
  • Rat Entrez ID: 502317
  • Catalogue Number171615
    Brand Family Calbiochem®
    References
    ReferencesWalsh D.M., et al. 2002. Biochemistry in press.
    Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
    von Koch, C.S., et al. 1997. Neurobiol. Aging 18, 661.
    Product Information
    FormLiquid
    FormulationUndiluted serum.
    PreservativeNone
    Applications
    Key Applications Immunoblotting (Western Blotting)
    Immunofluorescence
    Immunoprecipitation
    Application NotesImmunoblotting (1:5000-1:20,000)
    Immunofluorescence (1:250-1:500)
    Immunoprecipitation (1-2 µl/mg cell or tissue lysate)
    Application CommentsDoes not react with APP and APLP2. Variables associated with assay conditions will dictate the proper working dilution.
    Biological Information
    Immunogena synthetic peptide [(C)NPTYRFLEERP] corresponding to amino acids 643-653 of mouse APLP1, conjugated to KLH
    ImmunogenMouse
    HostRabbit
    IsotypeIgG
    Physicochemical Information
    Dimensions
    Materials Information
    Toxicological Information
    Safety Information according to GHS
    Safety Information
    Product Usage Statements
    Storage and Shipping Information
    Ship Code Dry Ice Only
    Toxicity Standard Handling
    Storage -20°C
    Avoid freeze/thaw Avoid freeze/thaw
    Do not freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Packaging Information
    Transport Information
    Supplemental Information
    Specifications

    Documentation

    Anti-β-Amyloid Precursor-Like Protein 1, C-Terminal (643-653) Rabbit pAb Certificates of Analysis

    TitleLot Number
    171615

    References

    Přehled odkazů
    Walsh D.M., et al. 2002. Biochemistry in press.
    Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
    von Koch, C.S., et al. 1997. Neurobiol. Aging 18, 661.

    Brochure

    Title
    Alzheimer's Disease Brochure & Technical Guide

    Citations

    Název
  • Meir H. Scheinfeld, et al. (2002) Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription. Journal of Biological Chemistry 277, 44195-44201.
  • Data Sheet

    Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

    Revision27-June-2007 RFH
    ApplicationImmunoblotting (1:5000-1:20,000)
    Immunofluorescence (1:250-1:500)
    Immunoprecipitation (1-2 µl/mg cell or tissue lysate)
    DescriptionRabbit polyclonal antibody supplied as undiluted serum. Recognizes the APLP1 protein.
    BackgroundAmyloid precursor-like protein 1 (APLP1) is a member of a family of related polypeptides that includes amyloid precursor proteins (APP) and amyloid precursor-like protein 2 (APLP2). APP generates β-amyloid peptide, deposits of which form the amyloid plaques that characterize Alzheimer's disease.
    HostRabbit
    Immunogen speciesMouse
    Immunogena synthetic peptide [(C)NPTYRFLEERP] corresponding to amino acids 643-653 of mouse APLP1, conjugated to KLH
    IsotypeIgG
    Specieshuman, mouse, rat
    FormLiquid
    FormulationUndiluted serum.
    PreservativeNone
    CommentsDoes not react with APP and APLP2. Variables associated with assay conditions will dictate the proper working dilution.
    Storage Avoid freeze/thaw
    -20°C
    Do Not Freeze Ok to freeze
    Special InstructionsFollowing initial thaw, aliquot and freeze (-20°C).
    Toxicity Standard Handling
    ReferencesWalsh D.M., et al. 2002. Biochemistry in press.
    Thinakaran, G., et al. 1998. Neurobiol. Dis. 4, 438.
    von Koch, C.S., et al. 1997. Neurobiol. Aging 18, 661.
    Citation
  • Meir H. Scheinfeld, et al. (2002) Processing of β-Amyloid Precursor-like Protein-1 and -2 by γ-Secretase Regulates Transcription. Journal of Biological Chemistry 277, 44195-44201.