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181205 Arachidonic Acid, Porcine Liver, Sodium Salt - CAS 6610-25-9 - Calbiochem

181205
  
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
6610-25-9C₂₀H₃₁O₂ · Na
Description
OverviewPrecursor for prostaglandins, prostacyclin, and thromboxane. Binds to G-protein α-subunits in a covalent, post-translational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets. Modulates nitric oxide production by prostaglandin synthesis via the cyclooxygenase pathway.
Catalogue Number181205
Brand Family Calbiochem®
Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, Na, 20:4
References
ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science 252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman, P., et al. 1986. Annu. Rev. Biochem. 55, 69.
Product Information
CAS number6610-25-9
ATP CompetitiveN
FormWhite crystalline solid
Hill FormulaC₂₀H₃₁O₂ · Na
Chemical formulaC₂₀H₃₁O₂ · Na
ReversibleN
Applications
Biological Information
Primary TargetRas-GAP
Purity≥99% by TLC and GC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
RTECSJX3874000
Safety Information
R PhraseR: 20/21/22-36/37/38

Harmful by inhalation, in contact with skin and if swallowed.
Irritating to eyes, respiratory system and skin.
S PhraseS: 36-26

Wear suitable protective clothing.
In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Harmful
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Arachidonic Acid, Porcine Liver, Sodium Salt - CAS 6610-25-9 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Arachidonic Acid, Porcine Liver, Sodium Salt - CAS 6610-25-9 - Calbiochem Certificates of Analysis

TitleLot Number
181205

References

Přehled odkazů
Hallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science 252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman, P., et al. 1986. Annu. Rev. Biochem. 55, 69.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-September-2007 RFH
Synonymscis,cis,cis,cis-5,8,11,14-Eicosatetraenoic Acid, Na, 20:4
DescriptionA cis-polyunsaturated fatty acid found in the plasma membrane. Major component of membrane phospholipids. Following its release by cellular phospholipases, it is enzymatically converted to a variety of inflammatory and vasoactive metabolites, such as prostaglandins (via the cyclooxygenase pathway), leukotrienes (via the lipoxygenase pathway), and epoxides (via the cytochrome P450 pathway). Binds to G-protein α-subunits in a covalent, posttranslational manner. Inhibits Ras-GAP. Stimulates the synthesis of nitric oxide by platelets.
FormWhite crystalline solid
Intert gas (Yes/No) Packaged under inert gas
CAS number6610-25-9
RTECSJX3874000
Chemical formulaC₂₀H₃₁O₂ · Na
Purity≥99% by TLC and GC
SolubilityH₂O (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsUnstable in solution; reconstitute just prior to use.
Toxicity Harmful
Merck USA index14, 765
ReferencesHallak, H., et al. 1994. J. Biol. Chem. 269, 4713.
Khurana, G., and Bennett, M.R. 1993. Br. J. Pharmacol. 109, 480.
Han, J.-W., et al. 1991. Science 252, 576.
Radomski, M.W., et al. 1990. Br. J. Pharmacol. 101, 325.
Neddleman, P., et al. 1986. Annu. Rev. Biochem. 55, 69.