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203696 BPIQ-I

203696
  
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Přehled

Replacement Information

Tabulka spec. kláve

CAS #Empirical Formula
174709-30-9C₁₆H₁₂BrN₅
Description
Overview

This product has been discontinued.





A cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM).
Catalogue Number203696
Brand Family Calbiochem®
Synonyms8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline
References
ReferencesRewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918.
Product Information
CAS number174709-30-9
ATP CompetitiveY
FormOff-white solid
Hill FormulaC₁₆H₁₂BrN₅
Chemical formulaC₁₆H₁₂BrN₅
ReversibleY
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetEGFR
Primary Target IC<sub>50</sub>25 pM against tyrosine kinase activity of the epidermal growth factor receptor (EGFR)
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

BPIQ-I Certificates of Analysis

TitleLot Number
203696

References

Přehled odkazů
Rewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-January-2010 RFH
Synonyms8-[(3-Bromophenyl)amino]-3-methyl-3H-imidazo[4,5-g]-quinazoline
DescriptionA cell-permeable, reversible, ATP-competitive, potent and specific inhibitor of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR; IC50 = 25 pM).
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number174709-30-9
Chemical formulaC₁₆H₁₂BrN₅
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (5 mg/ml)
Storage Protect from light
-20°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesRewcastle, G.W., et al. 1996. J. Med. Chem. 39, 918.