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203292 Bisindolylmaleimide II - CAS 137592-45-1 - Calbiochem

203292
  
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Tabulka spec. kláve

CAS #Empirical Formula
137592-45-1C₂₇H₂₆N₄O₂
Description
Overview

This product has been discontinued.



A potent, cell permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC50 = 13 nM). May inhibit protein kinase A at much higher concentrations (IC50 = 2 µM).

Catalogue Number203292
Brand Family Calbiochem®
Synonyms2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide
References
ReferencesToullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
Product Information
CAS number137592-45-1
ATP CompetitiveY
FormOrange solid
Hill FormulaC₂₇H₂₆N₄O₂
Chemical formulaC₂₇H₂₆N₄O₂
ReversibleY
Structure formula ImageStructure formula Image
Applications
Biological Information
Primary TargetPKC
Primary Target IC<sub>50</sub>13 nM against protein kinase C
Purity≥95% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Bisindolylmaleimide II - CAS 137592-45-1 - Calbiochem MSDS

Title

Safety Data Sheet (SDS) 

Bisindolylmaleimide II - CAS 137592-45-1 - Calbiochem Certificates of Analysis

TitleLot Number
203292

References

Přehled odkazů
Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-April-2011 RFH
Synonyms2-[1-[2-(1-Methylpyrrolidino)ethyl]-1H-indol-3-yl]-3-(1H-indol-3-yl)maleimide
DescriptionA potent, cell permeable, reversible, ATP-competitive and selective inhibitor of protein kinase C (IC50 = 13 nM). Also inhibits protein kinase A at much higher concentrations (IC50 = 2 µM).
FormOrange solid
CAS number137592-45-1
Chemical formulaC₂₇H₂₆N₄O₂
Structure formulaStructure formula
Purity≥95% by HPLC
SolubilityDMSO (50 mg/ml)
Storage +2°C to +8°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesToullec, D., et al. 1991. J. Biol. Chem. 266, 15771.