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203297 Bisindolylmaleimide IV - CAS 119139-23-0 - Calbiochem

203297
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Tabulka spec. kláve

Empirical FormulaCAS #
C₂₀H₁₃N₃O₂ 119139-23-0

Ceny a dostupnost

Katalogové číslo DostupnostBalení ks/bal. Cena Množství
203297-1MG
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      Vyžádat nacenění
      Description
      OverviewA potent, cell permeable, and selective inhibitor of protein kinase C (IC50 = 87 nM). Inhibits protein kinase A at much higher concentrations (IC50 = 2.7 µM).
      Catalogue Number203297
      Brand Family Calbiochem®
      SynonymsArcyriarubin A, 2,3-bis(1H-Indol-3-yl)maleimide, Ro 31-6233
      References
      ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
      Davis, P.D., et al. 1992. J. Med. Chem. 35, 177.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Product Information
      CAS number119139-23-0
      ATP CompetitiveN
      FormDark orange powder or solid
      Hill FormulaC₂₀H₁₃N₃O₂
      Chemical formulaC₂₀H₁₃N₃O₂
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary TargetPKC
      Primary Target IC<sub>50</sub>87 nM against protein kinase C
      Purity≥98% by TLC
      Physicochemical Information
      Cell permeableY
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage +2°C to +8°C
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Bisindolylmaleimide IV - CAS 119139-23-0 - Calbiochem MSDS

      Title

      Safety Data Sheet (SDS) 

      Bisindolylmaleimide IV - CAS 119139-23-0 - Calbiochem Certificates of Analysis

      TitleLot Number
      203297

      References

      Přehled odkazů
      Fabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
      Davis, P.D., et al. 1992. J. Med. Chem. 35, 177.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision15-February-2019 JSW
      SynonymsArcyriarubin A, 2,3-bis(1H-Indol-3-yl)maleimide, Ro 31-6233
      DescriptionA cell-permeable potent and selective inhibitor of protein kinase C (IC50 = 87 nM) and protein kinase A (IC50 = 2.7 µM).
      FormDark orange powder or solid
      CAS number119139-23-0
      Chemical formulaC₂₀H₁₃N₃O₂
      Structure formulaStructure formula
      Purity≥98% by TLC
      SolubilityMethanol (10 mg/ml)
      Storage +2°C to +8°C
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
      Toxicity Standard Handling
      ReferencesFabre, S., et al. 1993. Bioorg. Med. Chem. 1, 193.
      Davis, P.D., et al. 1992. J. Med. Chem. 35, 177.
      Toullec, D., et al. 1991. J. Biol. Chem. 266, 15771.