324800 Epoxomicin, Synthetic - Calbiochem

324800
Cenu nelze zjistit
Minimum Quantity needs to be mulitiple of
S dokončenou objednávkou Další informace
Ušetřili jste ()
 
Vyžádat nacenění
Omezená dostupnostOmezená dostupnost
Na skladě 
Přerušeno
Dostupné omezené množství
Dostupnost bude potvrzena
    Remaining : Will advise
      Remaining : Will advise
      Bude poskytnuto
      Kontaktujte Zákaznický servis
      Contact Customer Service
      Zobrazit ceny a dostupnost

      Přehled

      Replacement Information

      Tabulka spec. kláve

      Empirical Formula
      C₂₈H₅₀N₄O₇

      Ceny a dostupnost

      Katalogové číslo DostupnostBalení ks/bal. Cena Množství
      324800-100UG
      Zjišťuji dostupnost...
      Omezená dostupnostOmezená dostupnost
      Na skladě 
      Přerušeno
      Dostupné omezené množství
      Dostupnost bude potvrzena
        Remaining : Will advise
          Remaining : Will advise
          Bude poskytnuto
          Kontaktujte Zákaznický servis
          Contact Customer Service

          Skleněná láhev 100 μg
          Zjišťuji cenu...
          Cenu nelze zjistit
          Minimum Quantity needs to be mulitiple of
          S dokončenou objednávkou Další informace
          Ušetřili jste ()
           
          Vyžádat nacenění
          Description
          OverviewAn antitumor and anti-inflammatory agent that acts as a potent, highly specific, and irreversible inhibitor of chymotrypsin-like (CT-L), trypsin-like (T-L), and peptidyl-glutamyl peptide hydrolyzing (PGPH) activities of the proteasome. Modifies the proteasomal catalytic subunits LMP-7, MECL1, and Z. Does not affect the activities of non-proteasomal proteases such as trypsin, cathepsin B, or chymotrypsin. A 1 mM (50 µg/90 µl) solution of Epoxomicin, Synthetic (Cat. No. 324801) in DMSO is also available.
          Catalogue Number324800
          Brand Family Calbiochem®
          SynonymsProteasome Inhibitor XIV
          References
          ReferencesMeng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
          Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
          Hanada, M., et al. 1992. J. Antibiot. 45, 1746.
          Product Information
          ATP CompetitiveN
          FormWhite solid
          Hill FormulaC₂₈H₅₀N₄O₇
          Chemical formulaC₂₈H₅₀N₄O₇
          ReversibleN
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary TargetCT-L,T-L,PGPH activity of proteasome
          Purity≥95% by HPLC
          Physicochemical Information
          Cell permeableN
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage -20°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Canadian export regulations Due to the country and/or U.S. state of origin of the animal material used in this product, this product may not be exported to Canada.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Epoxomicin, Synthetic - Calbiochem MSDS

          Title

          Safety Data Sheet (SDS) 

          Epoxomicin, Synthetic - Calbiochem Certificates of Analysis

          TitleLot Number
          324800

          References

          Přehled odkazů
          Meng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
          Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
          Hanada, M., et al. 1992. J. Antibiot. 45, 1746.

          Brochure

          Title
          Caspases and other Apoptosis Related Tools Brochure
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision19-June-2008 RFH
          SynonymsProteasome Inhibitor XIV
          DescriptionAn antitumor agent of microbial origin that acts as a potent, highly specific, and irreversible inhibitor of chymotrypsin-like (CT-L), trypsin-like (T-L), and peptidylglutamyl peptide hydrolyzing (PGPH) activities of the proteasome. Modifies the proteasomal catalytic subunits LMP-7, MECL1, and Z. Epoxomicin also displays potent anti-inflammatory activity in vivo.
          FormWhite solid
          Intert gas (Yes/No) Packaged under inert gas
          Chemical formulaC₂₈H₅₀N₄O₇
          Structure formulaStructure formula
          Purity≥95% by HPLC
          SolubilityDMSO (1 mg/ml) or Methanol (1 mg/ml)
          Storage -20°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C.
          Toxicity Standard Handling
          ReferencesMeng, L., et al. 1999. Proc. Natl. Acad. Sci. USA 96, 10403.
          Sin, N., et al. 1999. Bioorg. Med. Chem. Lett. 9, 2283.
          Hanada, M., et al. 1992. J. Antibiot. 45, 1746.