371708 Gβγ Modulator II, Gallein - CAS 2103-64-2 - Calbiochem

371708
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      Přehled

      Replacement Information

      Tabulka spec. kláve

      Empirical FormulaCAS #
      C₂₀H₁₂O₇ • 2H₂O 2103-64-2

      Ceny a dostupnost

      Katalogové číslo DostupnostBalení ks/bal. Cena Množství
      371708-5MG
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          Plastová ampulka 5 mg
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          Vyžádat nacenění
          Description
          OverviewA cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Reported to exhibit in vivo prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model via either intraperitoneal or oral administration.
          Catalogue Number371708
          Brand Family Calbiochem®
          Synonyms4,5-Dihydroxyfluorescein, dihydrate, 2-(3,4,5-Trihydroxy-6-oxoxanthen-9-yl)-benzoic acid, dihydrate
          References
          ReferencesLehmann, D.M., et al. 2008. Mol. Pharmacol. 73, 410.
          Product Information
          CAS number2103-64-2
          FormBurgundy solid
          Hill FormulaC₂₀H₁₂O₇ • 2H₂O
          Chemical formulaC₂₀H₁₂O₇ • 2H₂O
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Purity≥90% by HPLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          S PhraseS: 22-24/25-37-45

          Do not breathe dust.
          Avoid contact with skin and eyes.
          Wear suitable gloves.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Ambient Temperature Only
          Toxicity Standard Handling
          Storage +2°C to +8°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Packaged under inert gas Packaged under inert gas
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Gβγ Modulator II, Gallein - CAS 2103-64-2 - Calbiochem MSDS

          Title

          Safety Data Sheet (SDS) 

          Gβγ Modulator II, Gallein - CAS 2103-64-2 - Calbiochem Certificates of Analysis

          TitleLot Number
          371708

          References

          Přehled odkazů
          Lehmann, D.M., et al. 2008. Mol. Pharmacol. 73, 410.
          Data Sheet

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision02-October-2008 RFH
          Synonyms4,5-Dihydroxyfluorescein, dihydrate, 2-(3,4,5-Trihydroxy-6-oxoxanthen-9-yl)-benzoic acid, dihydrate
          DescriptionA cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ~400 nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Reported to exhibit in vivo prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model via either intraperitoneal or oral administration.
          FormBurgundy solid
          Intert gas (Yes/No) Packaged under inert gas
          CAS number2103-64-2
          Chemical formulaC₂₀H₁₂O₇ • 2H₂O
          Structure formulaStructure formula
          Purity≥90% by HPLC
          SolubilityDMSO (10 mg/ml)
          Storage +2°C to +8°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Standard Handling
          ReferencesLehmann, D.M., et al. 2008. Mol. Pharmacol. 73, 410.