Millipore Sigma Vibrant Logo
Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

203678 PKG Substrate, BPDEtide

203678
  
Purchase on Sigma-Aldrich

Přehled

Replacement Information
Description
Overview

This product has been discontinued.





Sequence derived from bovine lung cGMP-specific phosphodiesterase (cG-BPDE). A specific and sensitive substrate for PKG (Km = 68 µM) relative to PKA (Km = 320 µM). Not phosphorylated by PKC or by CaM kinase II.
Catalogue Number203678
Brand Family Calbiochem®
SynonymsProtein Kinase G Substrate, RKISASEFDRPLR
References
ReferencesGertzberg, N., et al. 2000. Am. J. Respir. Cell Mol. Biol. 22, 105.
Patel, A.I., and Diamond, J. 1997. J. Pharmacol. Exp. Ther. 283, 885.
Colbran, J.L., et al. 1992. J. Biol. Chem. 267, 9589.
Corbin, J.D., and Døskeland, S.O. 1983. J. Biol. Chem. 258, 11391.
Product Information
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₆₈H₁₁₅N₂₃O₂₀
Chemical formulaC₆₈H₁₁₅N₂₃O₂₀
Hygroscopic Hygroscopic
Sold on the basis of peptide contentY
Applications
Biological Information
Purity≥95% by HPLC
Physicochemical Information
Peptide ContentY
Peptide SequenceH-Arg-Lys-Ile-Ser-Ala-Ser-Glu-Phe-Asp-Arg-Pro-Leu-Arg-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

PKG Substrate, BPDEtide Certificates of Analysis

TitleLot Number
203678

References

Přehled odkazů
Gertzberg, N., et al. 2000. Am. J. Respir. Cell Mol. Biol. 22, 105.
Patel, A.I., and Diamond, J. 1997. J. Pharmacol. Exp. Ther. 283, 885.
Colbran, J.L., et al. 1992. J. Biol. Chem. 267, 9589.
Corbin, J.D., and Døskeland, S.O. 1983. J. Biol. Chem. 258, 11391.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision04-January-2008 JSW
SynonymsProtein Kinase G Substrate, RKISASEFDRPLR
DescriptionSequence derived from bovine lung cGMP-specific phosphodiesterase (cG-BPDE). A specific substrate for PKG (Km = 68 µM) relative to PKA (Km = 320 µM). Not phosphorylated by PKC or by CaM kinase II.
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₆₈H₁₁₅N₂₃O₂₀
Peptide SequenceH-Arg-Lys-Ile-Ser-Ala-Ser-Glu-Phe-Asp-Arg-Pro-Leu-Arg-OH
Purity≥95% by HPLC
SolubilityH₂O (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGertzberg, N., et al. 2000. Am. J. Respir. Cell Mol. Biol. 22, 105.
Patel, A.I., and Diamond, J. 1997. J. Pharmacol. Exp. Ther. 283, 885.
Colbran, J.L., et al. 1992. J. Biol. Chem. 267, 9589.
Corbin, J.D., and Døskeland, S.O. 1983. J. Biol. Chem. 258, 11391.