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As leaders in cancer research, Merck scientists have developed a wide range of assays and reagents to help uncover apoptosis mechanisms and possible ways to induce apoptosis in tumor cells for therapeutic benefit.
Whether cells are in the early stages of apoptosis (with exposed inner leaflets), intermediate stages (with active caspase activity), or late stages (with extensive DNA fragmentation), Merck’s reagents and cell-based assays detect specific cell death processes across the apoptotic timeline.
Our apoptosis assays utilize all major detection methods, platforms and technologies, including (but not limited to) TUNEL assays, cell based assays, high content analysis, flow cytometry, and quantitative biomarker immunodetection; Merck’s versatile, innovative approach brings unprecedented depth and breadth to apoptosis research worldwide.