SAB4301136
Anti-c-Myc Tag antibody produced in rabbit
affinity isolated antibody
Sinónimos:
Myc Tag Antibody, Myc Tag Antibody - Anti-c-Myc Tag antibody produced in rabbit, c- Myc epitope Tag
Iniciar sesión para ver los precios por organización y contrato.
Seleccione un Tamaño
Cambiar Vistas
Acerca de este artículo
NACRES:
NA.43
UNSPSC Code:
12352203
Clone:
polyclonal
Technique(s):
western blot: 1:1000-1:5000 (Cell Lysate)
Application:
WB
Citations:
16
Servicio técnico
¿Necesita ayuda? Nuestro equipo de científicos experimentados está aquí para ayudarle.
Permítanos ayudarlebiological source
rabbit
Quality Segment
antibody form
affinity isolated antibody
antibody product type
primary antibodies
clone
polyclonal
form
buffered aqueous solution
mol wt
55 kDa
concentration
1 mg/mL
technique(s)
western blot: 1:1000-1:5000 (Cell Lysate)
isotype
IgG
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
General description
c-Myc (v-myc avian myelocytomatosis viral oncogene homolog) is a transcription factor, which is coded by MYC gene. It was first described as a homolog of an avian retroviral oncogene. It belongs to the family of transcription factors which are characterized by basic region helix-loop-helix/leucine zipper. Along with N-Myc and L-Myc, it forms the MYC proto-oncogene family. It forms a heterodimer with MAX, and this heterodimer binds to the E-boxes/CACGTG sequence motif on DNA. This gene is localized to human chromosome 8q24.
Immunogen
Synthetic peptide: C-EQKLISEEDL conjugated with KLH.
Application
Anti-c-Myc Tag antibody produced in rabbit has been used in western blotting.
Biochem/physiol Actions
The antibody detects transfected proteins contanining c-Myc Tag.
v-myc avian myelocytomatosis viral oncogene homolog belongs to MYC family. When overexpressed, these proteins can delay the resolution of DNA lesions and cause DNA double-strand breaks (DSBs) and genome instability. This transcription factor MYC helps in regulating long noncoding RNAs (lncRNAs), which has been implicated in cancer cell proliferation and tumorigenesis. Its overexpression is also associated with various cancers, and in particular B cell lymphomas. Elevated expression of c-MYC inhibits the ability of B cell lymphomas to functionally present antigens/peptides to CD4+ T cells. It is associated with Burkitt lymphoma and a group of diffuse large B-cell lymphoma (DLBCL).
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Still not finding the right product?
Pruebe nuestra Herramienta de selección de productos para limitar sus opciones
Clase de almacenamiento
10 - Combustible liquids
wgk
WGK 1
Elija entre una de las versiones más recientes:
¿Ya tiene este producto?
Encuentre la documentación para los productos que ha comprado recientemente en la Biblioteca de documentos.