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Merck

GF113

Sigma-Aldrich

Transforming Growth Factor-β2 human

>95% (SDS-PAGE), recombinant, expressed in Baculovirus infected High-5 cells suitable for cell culture

Synonym(s):

TGF-beta2

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About This Item

UNSPSC Code:
12352202
eCl@ss:
32160405
NACRES:
NA.75

Product Name

Transforming Growth Factor-β2 Protein, Recombinant human, Transforming Growth Factor-beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation & differentiation of normal & transformed cells.

biological source

human

Assay

>95% (SDS-PAGE)

specific activity

≥5 x 10e6 U/mg

manufacturer/tradename

Chemicon®

technique(s)

cell culture | mammalian: suitable

impurities

<0.1 ng/μg Endotoxin (of TGF-Beta2; 1EU/ug)

input

sample type mesenchymal stem cell(s)

NCBI accession no.

NM_003238.1

UniProt accession no.

P61812

shipped in

dry ice

Gene Information

human ... TGFB2(7042)

Related Categories

General description

Product Source: Baculovirus infected High-5 cells
Transforming Growth Factor- beta2 (TGF-beta2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. Human TGF-beta2 is a 25.0 kDa protein with each subunit containing 112 amino acid residues.

Biochem/physiol Actions

Determined by its ability to inhibit the mouse IL-4-dependent proliferation of mouse HT-2 cells.The ED(50) was found to be ≤0.2ng/ml

Physical form

Lyophilized from Sodium Citrate, pH 3.5.

Preparation Note

The lyophilized powder is stable for a few weeks at room temperature, but best stored at -20°C. Reconstitute with water to a concentration of 50 μg/ml (e.g., 5 μg/100 μl), this will yield a solution of 1 mM citrate buffer pH 3.5 This solution can then be stored at room temperature or at 2-8ºC for 1 month. It is recommended that further dilutions be made into PBS containing 2 mg/ml albumin and stored at -20ºC. Reconstituted human TGF-beta2 should be stored in undiluted aliquots at -20°C for at least 2 months. Avoid repeated freeze/thaw cycles.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Pictograms

Exclamation mark
GHS07

Signal Word

Warning

Hazard Statements

H319,H335

Hazard Classifications

Eye Irrit. 2 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 1

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Wisuwat Thongphichai et al.
BMC complementary medicine and therapies, 22(1), 139-139 (2022-05-19)
Crinum latifolium L. (Amaryllidaceae) has been used in Southeast Asian traditional medicine to alleviate the symptoms of benign prostatic hyperplasia (BPH). The pathological mechanism of BPH is associated with the induction of prostate stromal cell proliferation through transforming growth factor-beta
Rojo A Ratsimandresy et al.
Nature communications, 8, 15556-15556 (2017-06-06)
Inflammasomes are protein platforms linking recognition of microbe, pathogen-associated and damage-associated molecular patterns by cytosolic sensory proteins to caspase-1 activation. Caspase-1 promotes pyroptotic cell death and the maturation and secretion of interleukin (IL)-1β and IL-18, which trigger inflammatory responses to

Global Trade Item Number

SKUGTIN
GF11304053252733925

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