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Merck

RLI1MAG-92K

MILLIPLEX® Rat Liver Injury Panel

Configurable Rat Liver Injury 5-Plex Panel

Synonym(s):

Luminex® Rat Liver Toxicity Assay, Millipore Rat Liver Toxicity Assay, Rat Liver Injury Multiplex Panel

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Rat Liver Injury Panel, Configurable Rat Liver Injury 5-Plex Panel

species reactivity

rat

manufacturer/tradename

Milliplex®

Quality Level

packaging

1 ea of

assay range

accuracy: 77-92%
sensitivity: 0.021-4.038 ng/mL
(MinDC+2SD)

standard curve range: 0.02-15.0 ng/mL
(GSTα)

standard curve range: 0.04-30.0 ng/mL
(5′-NT/CD73)

standard curve range: 0.08-60.0 ng/mL
(GOT1)

standard curve range: 0.10-75.0 ng/mL
(ARG1)

standard curve range: 0.62-450.0 ng/mL
(SDH)

technique(s)

multiplexing: suitable

detection method

fluorometric (Luminex® xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

Luminex is a registered trademark of Luminex Corp
MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 5 analytes rat serum or plasma samples.

Analytes Included: 5′NT/CD73, ARG1, GOT1, GSTα, SDH

Assay Characteristics: Refer to the assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy

Disclaimer

For research use only. Not for use in diagnostic procedures.

Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Multiplex detection of 5 liver injury biomarkers in one assay
  • Magnetic bead-based format for efficient and reproducible processing
  • Compatible with rat serum, plasma, and tissue lysates
  • High sensitivity for early detection of hepatocellular damage
Benefits:

  • Conserves sample volume and reagents through multiplexing
  • Improves data quality and reproducibility with magnetic bead format
  • Enables early detection and monitoring of liver injury
  • Supports translational research in liver disease and toxicology

General description

5′NT/CD73 and ARG1 are markers of liver function and metabolic activity. GOT1 and SDH are enzymes released during hepatocellular injury, while GSTα reflects oxidative stress and detoxification. Together, these biomarkers provide a comprehensive view of liver damage and function in rat models.

pictograms

Skull and crossbonesEnvironment

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Irrit. 2 - Skin Sens. 1

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3


Certificates of Analysis (COA)

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Nalini Govender et al.
Clinical and experimental reproductive medicine, 48(2), 124-131 (2021-05-25)
Approximately 30% of preeclamptic pregnancies exhibit abnormal liver function tests. We assessed liver injury-associated enzyme levels and circulating transforming growth factor beta (TGF-β) levels in an arginine vasopressin (AVP)-induced pregnant Sprague-Dawley rat model. Pregnant and non-pregnant Sprague-Dawley rats (n=24) received

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Global Trade Item Number

SKUGTIN
RLI1MAG-92K-0104055977132670
RLI1MAG-92K-0304055977132694
RLI1MAG-92K-0204055977132687
RLI1MAG-92K-0504055977132717
RLI1MAG-92K-0404055977132700

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