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8.17003

Polyethylene glycol

400, EMPROVE® EXPERT, Ph. Eur., JP, NF

Synonym(s):

Poly(ethylene glycol), Polyglycol, Polyethylene oxide, Polyoxy ethylene, PEG 400, PEG

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About This Item

Linear Formula:
H(OCH2CH2)nOH
CAS Number:
25322-68-3
UNSPSC Code:
13111021
EC Index Number:
500-038-2
MDL number:
MFCD00081839
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Quality Level

500

agency

JP, NF, Ph. Eur.

vapor pressure

<0.1 hPa ( 20 °C)

product line

EMPROVE® EXPERT

form

liquid

autoignition temp.

360 °C (DIN 51794)

mol wt

average Mn 400

pH

5-7 (20 °C, 100 g/L in H2O)

kinematic viscosity

97-110 cSt(20 °C)

mp

5 °C

transition temp

flash point >200 °C

density

1.13 g/cm3 at 20 °C

application(s)

liquid formulation
ophthalmics
pharmaceutical
semi-solid formulation
solubility enhancement

storage temp.

15-25°C

SMILES string

C(CO)O

InChI

1S/C2H6O2/c3-1-2-4/h3-4H,1-2H2

InChI key

LYCAIKOWRPUZTN-UHFFFAOYSA-N

General description

When working on a pharmaceutical formulation, there are specific considerations to make and challenging hurdles to take before you can successfully launch your final drug product - formulation stability, release kinetics and bioavailability limitations just to name a few. With our application know-how and regulatory expertise, we support you in every step of development, scale-up, and production.
As part of our Emprove® Program, our raw materials are offered with extensive documentation facilitating compliance of your pharma and biopharma product, full supply chain transparency and risk mitigation. Our SAFC® portfolio of high-quality products for biopharmaceutical and pharmaceutical formulation and production withstands strict quality control procedures and is produced according to applicable cGMP guidelines.

Application

Polyethylene glycol (PEG) is a multipurpose polymer which can be applied in solid, semi-solid and liquid formulations. Its broad functional spectrum includes e.g. improvement of API solubility, acting as a lubricant for tablet coating, function as a carrier, and many more. Our comprehensive portfolio of PEGs comprises diverse polymer sizes of different molecular weights to meet your specific application and needs.

Legal Information

Emprove is a registered trademark of Merck KGaA, Darmstadt, Germany
SAFC is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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