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Merck

MAP2MAG-76K

MILLIPLEX® Mouse Acute Phase Panel 2

Configurable Mouse Acute Phase 6-Plex Panel 2

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About This Item

UNSPSC Code:
12161503
NACRES:
NA.84
eCl@ss:
32161000

Product Name

MILLIPLEX® Mouse Acute Phase Panel 2, Configurable Mouse Acute Phase 6-Plex Panel 2

species reactivity

mouse

manufacturer/tradename

Milliplex®

Quality Level

packaging

1 ea of

assay range

accuracy: 99.2-128.2%
sensitivity: 0.001-7.495 ng/mL
standard curve range: 0.001-0.5 ng/mL
(AGP)

standard curve range: 0.005-4.0 ng/mL
(Adipsin)

standard curve range: 0.014-10 ng/mL
(CRP)

standard curve range: 0.549-400 ng/mL
(Haptoglobin)

standard curve range: 13.717-10,000 ng/mL
(SAP)

standard curve range: 6.858-5000 ng/mL
(A2M)

inter-assay cv: <15%
intra-assay cv: <10%

technique(s)

multiplexing: suitable

input

cell culture supernatant(s)

detection method

fluorometric (Luminex xMAP® technology)

shipped in

wet ice

storage temp.

2-8°C

Legal Information

MILLIPLEX is a registered trademark of Merck KGaA, Darmstadt, Germany
xMAP is a registered trademark of Luminex Corp

Application

MILLIPLEX® Qualified assays undergo rigorous assay development, verification, and Quality Control testing to achieve optimal performance. Simultaneously analyze up to 6 analytes in mouse serum, plasma, or cell culture supernatants.

Analytes included: α-1-Acid Glycoprotein (AGP), α-2-Macroglobulin, Adipsin (Factor D), C-Reactive Protein (CRP), Haptoglobin, Serum Amyloid P (SAP).

Assay Characteristics: Refer to assay protocol for details on cross-reactivity, sensitivity, precision, and accuracy.

Disclaimer

For research use only. Not for use in diagnostic procedures.


Label License/Sticker for Assay Product:

By opening the packaging containing this Assay Product (which contains fluorescently labeled microsphere beads authorized by Luminex Corporation) or using this Assay Product in any manner, you are consenting and agreeing to be bound by the End User Terms and Conditions and the End User License Agreement available at http://support.diasorin.com/end-user-terms-and-conditions/. If you do not agree to all of the terms and conditions, you must promptly return this Assay Product for a full refund prior to using it in any manner.

Features and Benefits

Features:

  • Measures key metabolic hormones involved in energy regulation and glucose metabolism
  • Includes analytes such as insulin, leptin, ghrelin, adiponectin, and resistin
  • Enables simultaneous profiling for a comprehensive metabolic overview
  • Applicable to various biological samples like serum, plasma, and tissue extracts - Suitable for both research and clinical applications
Benefits:

  • Detects early signs of metabolic dysfunction such as insulin resistance and obesity
  • Supports evaluation of therapeutic interventions targeting metabolic pathways
  • Enhances understanding of hormonal interactions in metabolic disorders
  • Provides valuable data for tracking disease progression and recovery
  • Facilitates personalized approaches to managing metabolic health

General description

Metabolic hormones such as insulin, leptin, ghrelin, adiponectin, and resistin are central to regulating energy balance, appetite, and glucose metabolism. Insulin promotes cellular glucose uptake, leptin signals satiety, and ghrelin stimulates hunger, while adiponectin enhances insulin sensitivity and resistin contributes to inflammation and insulin resistance. Their coordinated activity reflects the body’s metabolic state and is crucial for understanding disorders like obesity and diabetes.

signalword

Danger

Hazard Classifications

Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Eye Dam. 1 - Skin Sens. 1 - STOT RE 2

target_organs

Respiratory Tract

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk

WGK 3


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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R B Kostogrys et al.
The journal of nutrition, health & aging, 19(7), 710-718 (2015-07-22)
Low Carbohydrate High Protein diet represents a popular strategy to achieve weight loss. The aim of this study was to characterize effects of low carbohydrate, high protein diet (LCHP) on atherosclerotic plaque development in brachiocephalic artery (BCA) in apoE/LDLR-/- mice
Edward O List et al.
Molecular endocrinology (Baltimore, Md.), 27(3), 524-535 (2013-01-26)
GH receptor (GHR) gene-disrupted mice (GHR-/-) have provided countless discoveries as to the numerous actions of GH. Many of these discoveries highlight the importance of GH in adipose tissue. For example GHR-/- mice are insulin sensitive yet obese with preferential
Marnix Lameijer et al.
Nature biomedical engineering, 2(5), 279-292 (2019-04-03)
Macrophage accumulation in atherosclerosis is directly linked to the destabilization and rupture of plaque, causing acute atherothrombotic events. Circulating monocytes enter the plaque and differentiate into macrophages, where they are activated by CD4+ T lymphocytes through CD40-CD40 ligand signalling. Here
Sarah M Snyder et al.
The Journal of nutrition, 146(5), 1001-1007 (2016-04-08)
Intake of polyphenols and polyphenol-rich fruit extracts has been shown to reduce markers of inflammation, diabetes, and hepatic complications that result from the consumption of a high-fat (HF) diet. The objective of this study was to determine whether mice fed
Damir Nizamutdinov et al.
Scientific reports, 7, 40112-40112 (2017-01-21)
Annually, there are over 2 million incidents of traumatic brain injury (TBI) and treatment options are non-existent. While many TBI studies have focused on the brain, peripheral contributions involving the digestive and immune systems are emerging as factors involved in

Global Trade Item Number

SKUGTIN
MAP2MAG-76K-0304053252797736
MAP2MAG-76K-0604053252799112
MAP2MAG-76K-0204053252797729
MAP2MAG-76K-0404053252797743
MAP2MAG-76K-0504053252797750
MAP2MAG-76K-0104053252797712

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