Caustic Alkalis & Bases
Life sciences encompass a wide range of activities—from complex chemical syntheses and analytical chemistry to routine laboratory work and large-scale production. Each application is governed by distinct regulatory requirements, making it essential to choose the right chemical products for your specific needs.
To simplify your search, we offer caustic alkalis and bases through three specialized portfolio brands, each tailored to a unique application area:
- Sigma-Aldrich® – Designed for general lab use and production environments.
- Supelco® – Ideal for analytical chemistry and precise laboratory testing.
- SAFC® – products for biopharmaceutical and pharmaceutical development and manufacturing
Each brand provides a broad selection of alkalis and bases available in various volumes, packaging formats, and with all necessary documentation to meet compliance standards. Whether you're working in research, development, or production, you can easily find the right product to match your application and regulatory requirements.
Explore our portfolio to find the best solution for your life sciences workflow.
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Organic and Inorganic Bases for Chemical Synthesis and Laboratory Use
Organic and inorganic bases are available in multiple grades, tailored for everything from general laboratory use to sensitive chemical syntheses including the synthesis of GLP-1 agonists.
- Reagent-grade bases (≥95% purity): For general synthesis, routine lab work, and research.
- ACS-grade bases: Reliable quality for synthesis, lab use, and analyses for publication.
- ReagentPlus® bases (≥98.5% purity): Ideal for trial syntheses and intermediate compounds.
- Puriss p.a. and Purum-grade bases: Ultra-pure, metal-tested bases for sensitive syntheses.
- Redi-Dri®anhydrous bases: Free-flowing, non-hygroscopic powders for efficient lab workflows.
Caustic Alkalis and Bases for Sample Preparation and Analysis
Explore our range of EMSURE® and EMPLURA® caustic alkalis and bases available in various concentrations, quality grades, and packaging sizes. This includes sodium and potassium hydroxide pellets, solutions, and ammonia solutions designed to meet your analytical needs. Manufactured in a dedicated facility with top-tier raw materials and advanced technology, our NaOH and KOH pellets ensure uniform pellet sizes and minimal impurities. Enjoy high purity and consistent batch-to-batch quality for reliable, reproducible results.
EMPLURA® caustic alkalis and bases
For preparative work and cleaning, choose EMPLURA® caustic alkalis and bases, which offer essential specifications at a competitive price.
EMSURE® Caustic Alkalis and Bases for Pharmacopoeia Analysis
EMSURE® caustic alkalis and bases are premium-grade products meet and even exceed global quality guidelines, including ACS and Reag. Ph Eur standards, ensuring broad acceptance in pharmaceutical quality control, simplifying audits, and reducing validation efforts and costs. Produced with high purity and batch-to-batch consistency, our caustic alkalis (NaOH and KOH pellets) deliver reliable, reproducible analytical results. They are available in various packaging sizes to accommodate diverse application needs.
High Purity Bases for Chromatography and Spectrometry
Lichropur high purity bases for HPLC and LC-MS analysis:
LiChropur® high purity bases are used in HPLC and LC-MS analysis to minimize background noise and signal suppression. These bases are application-tested by our quality control to meet our customers’ expectations.
Suprapur® and UltraPur® high-purity bases for ICP-OES, ICP-MS, AAS analysis
Suprapur® and Ultrapur® high-purity bases are used for inorganic trace and ultra-trace analysis. Each one of our analytical reagents is manufactured to clear the guaranteed specifications. The large variety of modern analytical methods (ICP-OES, ICP-MS, AAS, etc.) allow tailored control and analysis procedures for each product.
Volumetric solutions for Titration
Our Titripur® volumetric solutions and our Titrisol® concentrates offer a range of alkaline solution in different concentrations for quantifying compounds with the titration method. They are produced and analyzed under high-quality standards. The Titripur® solutions are analyzed by our DIN EN ISO/IEC 17025 accredited quality control lab. An innovation are our digital products with an RFID tag on the bottles to transfer data seamlessly.
Biopharmaceutical and pharmaceutical formulation and production products
Achieving consistent quality and regulatory compliance in biopharmaceutical manufacturing requires reliable raw materials and robust documentation. Our SAFC® portfolio provides high-purity process chemicals, solvents, and reagents manufactured under strict cGMP guidelines to support every stage from development and scale-up to commercial production. Through our Emprove® Program, each product is backed by comprehensive documentation that simplifies qualification, risk assessment, and regulatory submissions while ensuring full supply-chain transparency. With our technical expertise and customizable manufacturing options, we help you streamline process development and maintain confidence in your formulation and production workflows. Explore our Emprove® Chemicals portfolio and our complete range of bioprocessing and formulation raw materials to support your pharmaceutical and biopharmaceutical production needs.
Related Resources
- Brochure: Empower your Lab - Inorganics & Solvents for Classical Analysis
Discover how our Inorganics and Solvents can empower your work.
- Article: Emprove®
Emprove® Program streamlines compliance with technical, regulatory, and supply information in Emprove® Dossiers, supporting risk assessment.
- Flyer: Arcofolin™ L-Methylfolate Empowered by Nature
Experience the next-level folate.
- Brochure: Inorganics on Tap - Withdrawal Systems and Safety Accessories for Acids & Bases
For maximum safety in daily work with acids & bases.
- Flyer: Redi-Dri Free-Flowing Salts And Buffers
Redi-Dri™ free-flowing, ready-to-use salts and buffers don’t harden or clump like most hygroscopic powders. They just keep your work flowing.
- Brochure: SUPRAPUR® Acids and Bases
Quality grades for your individual needs.
- Guide: Titration Guide for Titer Determination
The titer determination of volumetric solutions is one of the most important preconditions to receive reliable and transparent results in titration.
- Brochure: Brighter Titration
Volumetric solutions and standards for titration accuracy and precision, every time
- Brochure: Extran Detergents - The Perfect Solution for Cleaning your Laboratory Utensils
Extran® detergents are a reliable cleaning agent of consistent composition that ensures proper scientific working procedures and avoids a frequently modification of processes and applications.
- Brochure: Reliable Research Must-Haves
This comprehensive guide explains the differences between the grades and outlines common applications for each specification – to make your decisions easier, and your work smoother.
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