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218746 Caspase-1 Inhibitor VI - Calbiochem

218746
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₁H₃₉FN₄O₉

Products

Catalogue NumberPackaging Qty/Pack
218746-1MG Glass bottle 1 mg
218746-250UG Plastic ampoule 250 μg
Description
OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE), caspase-4, and caspase-5.
Catalogue Number218746
Brand Family Calbiochem®
SynonymsZ-YVAD-FMK
References
ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.
Product Information
ATP CompetitiveN
FormWhite powder
Hill FormulaC₃₁H₃₉FN₄O₉
Chemical formulaC₃₁H₃₉FN₄O₉
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary Targetcaspase-1
Purity≥95% by HPLC or TLC
Physicochemical Information
Cell permeableY
Peptide SequenceZ-Tyr-Val-Ala-Asp(OMe)-CH₂F*
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Caspase-1 Inhibitor VI - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Caspase-1 Inhibitor VI - Calbiochem Certificates of Analysis

TitleLot Number
218746

References

Reference overview
Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision06-February-2018 JSW
SynonymsZ-YVAD-FMK
DescriptionA potent, cell-permeable and irreversible inhibitor of caspase-1 (ICE).
FormWhite powder
Chemical formulaC₃₁H₃₉FN₄O₉
Peptide SequenceZ-Tyr-Val-Ala-Asp(OMe)-CH₂F*
Structure formulaStructure formula
Purity≥95% by HPLC or TLC
SolubilityDMSO (5 mg/ml)
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
Toxicity Standard Handling
ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.