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219372 Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem

219372
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Overview

Replacement Information

Key Spec Table

Empirical FormulaCAS #
C₃₆H₃₃N₂O₆P429676-93-7

Products

Catalogue NumberPackaging Qty/Pack
219372-1MG Plastic ampoule 1 mg
Description
OverviewA potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G [IC50 = 53 nM and Ki = 63 nM]. Weakly inhibits chymotrypsin (Ki = 1.5 µM) and poorly inhibits thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
Catalogue Number219372
Brand Family Calbiochem®
References
ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
Product Information
CAS number429676-93-7
ATP CompetitiveN
FormWhite solid
Hill FormulaC₃₆H₃₃N₂O₆P
Chemical formulaC₃₆H₃₃N₂O₆P
ReversibleY
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
ApplicationCathepsin G Inhibitor I, CAS 429676-93-7, is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM).
Biological Information
Primary Targetcathepsin G
Primary Target IC<sub>50</sub>53 nM
Primary Target K<sub>i</sub>63 nM for cathepsin G
Purity≥98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Cathepsin G Inhibitor I - CAS 429676-93-7 - Calbiochem Certificates of Analysis

TitleLot Number
219372

References

Reference overview
Greco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-April-2011 RFH
DescriptionA potent, selective, reversible, and competitive non-peptide inhibitor of cathepsin G (IC50 = 53 nM and Ki = 63 nM). Weakly inhibits chymotrypsin (Ki = 1.5 µM) and does not have any significant inhibitory effect on thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase (IC50 > 100 µM).
FormWhite solid
Intert gas (Yes/No) Packaged under inert gas
CAS number429676-93-7
Chemical formulaC₃₆H₃₃N₂O₆P
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (5 mg/ml) or Methanol
Storage -20°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesGreco, M.N., et al. 2002. J. Am. Chem. Soc. 124, 3810.