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324744 Elastase Inhibitor II - Calbiochem

324744
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₂₀H₃₁ClN₄O₇

Products

Catalogue NumberPackaging Qty/Pack
324744-5MG Plastic ampoule 5 mg
Description
OverviewA potent irreversible inhibitor of human neutrophil elastase (HNE). Inhibition results from cross-linking of the catalytic residues His57 and Ser195.
Catalogue Number324744
Brand Family Calbiochem®
SynonymsHNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
References
ReferencesNavia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem. 262, 17178.
Product Information
ATP CompetitiveN
FormWhite lyophilized solid
Hill FormulaC₂₀H₃₁ClN₄O₇
Chemical formulaC₂₀H₃₁ClN₄O₇
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetHuman neutrophil elastase (HNE)
Purity≥99% by TLC
Physicochemical Information
Cell permeableN
Peptide SequenceMeOSuc-Ala-Ala-Pro-Ala-CMK
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Moisture Protect from moisture
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Elastase Inhibitor II - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Elastase Inhibitor II - Calbiochem Certificates of Analysis

TitleLot Number
324744

References

Reference overview
Navia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem. 262, 17178.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision20-October-2009 JSW
SynonymsHNE Inhibitor, MeOSuc-AAPA-CMK, MSACK
DescriptionA potent inhibitor of human neutrophil elastase (HNE).The inhibition results from cross-linking of catalytic residues His57 and Ser195 in the HNE in the presence of this inhibitor.
FormWhite lyophilized solid
Chemical formulaC₂₀H₃₁ClN₄O₇
Peptide SequenceMeOSuc-Ala-Ala-Pro-Ala-CMK
Structure formulaStructure formula
Purity≥99% by TLC
SolubilityDMSO (10 mg/ml) or Methanol
Storage -20°C
Protect from moisture
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze at -20°C. Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesNavia, M.A., et al. 1989. Proc. Natl. Acad. Sci. USA 86, 7.
Williams, H.R., et al. 1987. J. Biol. Chem. 262, 17178.