Attention: We have moved. Merck Millipore products are no longer available for purchase on MerckMillipore.com.Learn More

368059 Granzyme B Substrate II, Fluorogenic - Calbiochem

368059
Purchase on Sigma-Aldrich

Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
368059-1MG Plastic ampoule 1 mg
368059-5MG Plastic ampoule 5 mg
Description
OverviewA fluorogenic substrate for the detection of granzyme B and caspase-8 activity. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Catalogue Number368059
Brand Family Calbiochem®
SynonymsZ-IETD-AFC, Caspase-8 Substrate II
References
ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.
Product Information
ATP CompetitiveN
FormWhite lyophilized solid
Hill FormulaC₃₇H₄₂F₃N₅O₁₃
Chemical formulaC₃₇H₄₂F₃N₅O₁₃
ReversibleN
Quality LevelMQ100
Applications
Biological Information
Primary TargetFluorogenic substrate for the detection of granzyme B and caspase-8 activity
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Emission max.
Excitation max.
Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Granzyme B Substrate II, Fluorogenic - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Granzyme B Substrate II, Fluorogenic - Calbiochem Certificates of Analysis

TitleLot Number
368059

References

Reference overview
Karahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.

Brochure

Title
Caspases and other Apoptosis Related Tools Brochure
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision07-July-2008 RFH
SynonymsZ-IETD-AFC, Caspase-8 Substrate II
DescriptionA fluorogenic substrate for the detection of granzyme B. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
FormWhite lyophilized solid
Chemical formulaC₃₇H₄₂F₃N₅O₁₃
Peptide SequenceZ-Ile-Glu-Thr-Asp-AFC
Purity≥97% by HPLC
SolubilityDMSO (1 mg/ml)
Storage -20°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Standard Handling
ReferencesKarahashi, H., and Amano, F. 2000. Biol. Pharm. Bull. 23, 140.