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370665 Guanosine-3ʹ-5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Triethylammonium Salt - Calbiochem

370665
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH

Products

Catalogue NumberPackaging Qty/Pack
370665-25UMOL Plastic ampoule 25 umol
Description
OverviewSelective membrane-permeable activator of protein kinase G that has a higher activation potential than cGMP. Does not significantly affect cGMP-regulated phosphodiesterases. Inhibits the thrombin-induced phosphorylation of human platelets mediated by myosin light chain kinase (MLCK) and protein kinase C (PKC). Note: 25 µmol = 14.73 mg.
Catalogue Number370665
Brand Family Calbiochem®
Synonyms8-pCPT-cGMP, TEA
References
ReferencesAlioua, A., et al. 1998. J. Biol. Chem. 273, 32950.
Draijer, R., et al. 1995. Circ. Res. 77, 895.
Geiger, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 1031.
Wolfe, L., et al. 1989. J. Biol. Chem. 264, 7734.
Product Information
ATP CompetitiveN
FormLyophilized
Hill FormulaC₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH
Chemical formulaC₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetProtein kinase G
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Guanosine-3ʹ-5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Triethylammonium Salt - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Guanosine-3ʹ-5ʹ-cyclic Monophosphate, 8-(4-Chlorophenylthio)-, Triethylammonium Salt - Calbiochem Certificates of Analysis

TitleLot Number
370665

References

Reference overview
Alioua, A., et al. 1998. J. Biol. Chem. 273, 32950.
Draijer, R., et al. 1995. Circ. Res. 77, 895.
Geiger, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 1031.
Wolfe, L., et al. 1989. J. Biol. Chem. 264, 7734.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision08-July-2008 RFH
Synonyms8-pCPT-cGMP, TEA
DescriptionSelective membrane-permeable activator of protein kinase G. Has a higher activation potential than cGMP. Does not significantly affect cGMP-regulated phosphodiesterases. Inhibits the thrombin-induced phosphorylation of human platelets mediated by myosin light chain kinase (MLCK) and protein kinase C (PKC). Note: 25 µmol = 14.73 mg
FormLyophilized
Chemical formulaC₁₆H₁₄ClN₅O₇PS · (CH₃CH₂)₃NH
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (1 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Toxicity Standard Handling
ReferencesAlioua, A., et al. 1998. J. Biol. Chem. 273, 32950.
Draijer, R., et al. 1995. Circ. Res. 77, 895.
Geiger, J., et al. 1992. Proc. Natl. Acad. Sci. USA 89, 1031.
Wolfe, L., et al. 1989. J. Biol. Chem. 264, 7734.