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422686 Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem

422686
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Overview

Replacement Information

Products

Catalogue NumberPackaging Qty/Pack
422686-1MG Plastic ampoule 1 mg
Description
OverviewNative, single chain, high molecular weight Kininogen from human plasma. Nonenzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor α-XIIa. Also circulates in plasma in complex with Factor XI and may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
Catalogue Number422686
Brand Family Calbiochem®
References
ReferencesWeisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
Product Information
FormLiquid
FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Quality LevelMQ100
Applications
Biological Information
Purity≥95% by SDS-PAGE
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label Please refer to vial label for lot-specific concentration
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Standard Handling
Storage ≤ -70°C
Avoid freeze/thaw Avoid freeze/thaw
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Kininogen, High Molecular Weight, Single Chain, Human Plasma - Calbiochem Certificates of Analysis

TitleLot Number
422686

References

Reference overview
Weisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision05-August-2008 RFH
DescriptionNative, single chain, high molecular weight Kininogen from human plasma. Non-enzymatic cofactor of the contact activation system. Links prekallikrein to negatively charged surfaces, thereby allowing activation to kallikrein by surface-bound Factor a-XIIa. Also circulates in plasma in complex with Factor XI, that may play a role in the activation of Factor XI to Factor XIa by Factor α-XIIa. Serves as a source of bradykinin, a potent vasoactive peptide important in hypotension studies.
FormLiquid
FormulationIn 150 mM NaCl, 4 mM sodium acetate buffer, pH 5.3.
Concentration Label Please refer to vial label for lot-specific concentration
SourcePrepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity≥95% by SDS-PAGE
Storage ≤ -70°C
Avoid freeze/thaw
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Standard Handling
ReferencesWeisel, J.W., et al. 1994. J. Biol. Chem. 269, 10100.