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434625 Leukotriene B₄ - CAS 71160-24-2 - Calbiochem

434625
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
71160-24-2C₂₀H₃₂O₄

Products

Catalogue NumberPackaging Qty/Pack
434625-50UG Alu drum 50 μg
Description
OverviewPotent proinflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema and asthma.
Catalogue Number434625
Brand Family Calbiochem®
SynonymsLTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid
References
ReferencesKendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.
Product Information
CAS number71160-24-2
ATP CompetitiveN
FormLiquid
FormulationSupplied as oil dissolved in ethanol at 50 µg/ml.
Hill FormulaC₂₀H₃₂O₄
Chemical formulaC₂₀H₃₂O₄
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetPolymorphonuclear leukocytes
Purity>98% by HPLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 11

Highly flammable.
S PhraseS: 16-7

Keep away from sources of ignition - No Smoking.
Keep container tightly closed.
Product Usage Statements
Storage and Shipping Information
Ship Code Dry Ice Only
Toxicity Flammable
Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
Storage ≤ -70°C
Do not freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

Leukotriene B₄ - CAS 71160-24-2 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Leukotriene B₄ - CAS 71160-24-2 - Calbiochem Certificates of Analysis

TitleLot Number
434625

References

Reference overview
Kendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.

Brochure

Title
Bioactive Lipids Technical Bulletin
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision12-December-2019 JSW
SynonymsLTB₄, 5(S),12(R)-Dihydroxy-6-cis-8-trans-10-trans-14-cis-eicosatetraenoic Acid
DescriptionPotent inflammatory agent, primarily because of its actions on polymorphonuclear leukocytes that include chemotaxis, aggregation, degranulation, and stimulation of adherence to vascular endothelium. Stimulates c-fos and c-jun proto-oncogene transcription in human monocytes. Involved in the pathogenesis of postischemic cerebral edema.
FormLiquid
FormulationSupplied as oil dissolved in ethanol at 50 µg/ml.
CAS number71160-24-2
Chemical formulaC₂₀H₃₂O₄
Structure formulaStructure formula
Purity>98% by HPLC
Storage ≤ -70°C
Do Not Freeze Ok to freeze
Special InstructionsFollowing initial thaw, aliquot and freeze (-70°C).
Toxicity Flammable
Merck USA index14, 5455
ReferencesKendall, A.P., et al. 1995. Anesthesia 50, 590.
Dokter, W.H., et al. 1994. Leukemia 8, 1181.
Jedlitschky, G., et al. 1991. J. Biol. Chem. 266, 24763.