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444800 Meloxicam - CAS 71125-38-7 - Calbiochem

444800
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Overview

Replacement Information

Key Spec Table

CAS #Empirical Formula
71125-38-7C₁₄H₁₃N₃O₄S₂

Products

Catalogue NumberPackaging Qty/Pack
444800-100MG Plastic ampoule 100 mg
Description
OverviewA cell-permeable, non-steroidal anti-inflammatory drug (NSAID) of the oxicam family which preferentially inhibits the inducible isoform of COX-2 (IC50 = 4.7 µM) relative to COX-1 (IC50 = 36.6 µM). Also inhibits the growth of colorectal cancer cells in vitro.
Catalogue Number444800
Brand Family Calbiochem®
Synonyms4-Hydroxy-2-methyl-N-(5-methyl-2-thiazoyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
References
ReferencesBlanco, F.J., et al. 1999. J. Rheumatol. 26, 1366.
Davies, N.M., and Skjodt, N.M. 1999. Clin. Pharmacokinet. 36, 115.
Goldman, A.P., et al. 1998. Carcinogenesis 19, 2195.
Product Information
CAS number71125-38-7
ATP CompetitiveN
FormOff-white solid
Hill FormulaC₁₄H₁₃N₃O₄S₂
Chemical formulaC₁₄H₁₃N₃O₄S₂
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetCOX-2
Primary Target IC<sub>50</sub>4.7 µM, 36.6 µM against the inducible isoform of COX-2 relative to COX-1, respectively
Purity≥98% by HPLC
Physicochemical Information
Cell permeableY
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage +2°C to +8°C
Protect from Light Protect from light
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C.
Packaging Information
Packaged under inert gas Packaged under inert gas
Transport Information
Supplemental Information
Specifications

Documentation

Meloxicam - CAS 71125-38-7 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

Meloxicam - CAS 71125-38-7 - Calbiochem Certificates of Analysis

TitleLot Number
444800

References

Reference overview
Blanco, F.J., et al. 1999. J. Rheumatol. 26, 1366.
Davies, N.M., and Skjodt, N.M. 1999. Clin. Pharmacokinet. 36, 115.
Goldman, A.P., et al. 1998. Carcinogenesis 19, 2195.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision15-May-2008 RFH
Synonyms4-Hydroxy-2-methyl-N-(5-methyl-2-thiazoyl)-2H-1,2-benzothiazine-3-carboxamide-1,1-dioxide
DescriptionA cell-permeable, non-steroidal, anti-inflammatory drug (NSAID) of the oxicam family that preferentially inhibits the inducible isoform of cyclooxygenase-2 (COX-2; IC50 = 4.7 µM) relative to cyclooxygenase-1 (COX-1; IC50 = 36.6 µM). Also inhibits the growth of colorectal cancer cells in vitro.
FormOff-white solid
Intert gas (Yes/No) Packaged under inert gas
CAS number71125-38-7
Chemical formulaC₁₄H₁₃N₃O₄S₂
Structure formulaStructure formula
Purity≥98% by HPLC
SolubilityDMSO (10 mg/ml)
Storage +2°C to +8°C
Protect from light
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for 3 months at -20°C.
Toxicity Standard Handling
Merck USA index14, 5826
ReferencesBlanco, F.J., et al. 1999. J. Rheumatol. 26, 1366.
Davies, N.M., and Skjodt, N.M. 1999. Clin. Pharmacokinet. 36, 115.
Goldman, A.P., et al. 1998. Carcinogenesis 19, 2195.