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481486 NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem

481486
Purchase on Sigma-Aldrich

Overview

Replacement Information

Key Spec Table

Empirical Formula
C₁₂₃H₂₁₅N₃₃O₃₀S

Products

Catalogue NumberPackaging Qty/Pack
481486-500UG Plastic ampoule 500 μg
Description
OverviewAn inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Asn for Lys363 and Gly for Arg364 in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.
Catalogue Number481486
Brand Family Calbiochem®
Synonyms(AAVALLPAVLLALLAPVQRNGQKLMP)
References
ReferencesLin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
Product Information
ATP CompetitiveN
DeclarationSold under license of U.S. Patents 5,807,746 and 6,043,339 for research use only. Licenses for commercial manufacture, commercial use, diagnostics, or therapeutics may be obtained by contacting Vanderbilt University, Nashville, Tennessee.
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Hill FormulaC₁₂₃H₂₁₅N₃₃O₃₀S
Chemical formulaC₁₂₃H₂₁₅N₃₃O₃₀S
Hygroscopic Hygroscopic
ReversibleN
Sold on the basis of peptide contentY
Quality LevelMQ100
Applications
Biological Information
Primary Targetan inactive control for SN50 peptide
Purity≥97% by HPLC
Physicochemical Information
Cell permeableN
Peptide ContentY
Peptide SequenceH-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Standard Handling
Storage -20°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

NF-κB SN50M, Cell-Permeable Inactive Control Peptide - Calbiochem Certificates of Analysis

TitleLot Number
481486

References

Reference overview
Lin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision03-March-2008 JSW
Synonyms(AAVALLPAVLLALLAPVQRNGQKLMP)
DescriptionAn inactive control for SN50 peptide (Cat. No. 481480). Corresponds to the SN50 peptide sequence with substitutions of Lys363 for Asn and Arg364 for Gly in the NLS region. In murine endothelial LE-II cells induced by LPS, this peptide had no measurable effect on NF-κB translocation at 18 µM.
FormLyophilized
FormulationSupplied as a trifluoroacetate salt.
Chemical formulaC₁₂₃H₂₁₅N₃₃O₃₀S
Peptide SequenceH-Ala-Ala-Val-Ala-Leu-Leu-Pro-Ala-Val-Leu-Leu-Ala-Leu-Leu-Ala-Pro-Val-Gln-Arg-Asn-Gly-Gln-Lys-Leu-Met-Pro-OH
Purity≥97% by HPLC
SolubilityH₂O (5 mg/ml)
Storage -20°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C. Avoid/freeze thaw cycles of solutions.
Toxicity Standard Handling
ReferencesLin, Y.-Z., et al. 1995. J. Biol. Chem. 270, 14255.