504746 Idazoxan Hydrochloride - CAS 79944-56-2 - Calbiochem

504746
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      Replacement Information

      Tableau de caractéristiques principal

      Empirical FormulaCAS #
      C₁₁H₁₂N₂O₂ • HCl 79944-56-2

      Prix & Disponibilité

      Référence DisponibilitéConditionnement Qté Prix Quantité
      5047460001
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      Disponibilité limitéeDisponibilité limitée
      En stock 
      Interrompu(e)
      Disponible en quantités limitées
      Disponibilité à confirmer
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          Flacon en verre 50 mg
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          Description
          OverviewA non-selective antagonist for α2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for α2A, α2B, and α2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors.
          Catalogue Number504746
          Brand Family Calbiochem®
          Synonyms2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride, RX781094, Idazoxa, α₂-Adrenoceptor Antagonist, Idazoxan Hydrochloride
          References
          ReferencesHumpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
          Dabir, l., 1986. J.Pharmacol. 17, 113.
          Michel, M., et al. 1992. TIPS 13, 369.
          Eglen, R., et al. 1998. TiPS 19, 381.
          Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
          Gadie, B., 1984. Br J Pharmacol. 83, 707.
          Product Information
          CAS number79944-56-2
          FormWhite powder
          Hill FormulaC₁₁H₁₂N₂O₂ • HCl
          Chemical formulaC₁₁H₁₂N₂O₂ • HCl
          Structure formula ImageStructure formula Image
          Quality LevelMQ100
          Applications
          Biological Information
          Primary Target→₂-adrenoceptor
          Purity≥98% by TLC
          Physicochemical Information
          Dimensions
          Materials Information
          Toxicological Information
          Safety Information according to GHS
          Safety Information
          R PhraseR: 25

          Toxic if swallowed.
          S PhraseS: 22-36-45

          Do not breathe dust.
          Wear suitable protective clothing.
          In case of accident or if you feel unwell, seek medical advice immediately (show the label where possible).
          Product Usage Statements
          Storage and Shipping Information
          Ship Code Shipped at Ambient Temperature or with Blue Ice or with Dry Ice
          Toxicity Toxic
          Hazardous Materials Attention: Due to the nature of the Hazardous Materials in this shipment, additional shipping charges may be applied to your order. Certain sizes may be exempt from the additional hazardous materials shipping charges. Please contact your local sales office for more information regarding these charges.
          Storage +15°C to +30°C
          Protect from Light Protect from light
          Do not freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
          Packaging Information
          Transport Information
          Supplemental Information
          Specifications

          Documentation

          Idazoxan Hydrochloride - CAS 79944-56-2 - Calbiochem FDS

          Titre

          Fiche de données de sécurité des matériaux (FDS) 

          Références bibliographiques

          Aperçu de la référence bibliographique
          Humpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
          Dabir, l., 1986. J.Pharmacol. 17, 113.
          Michel, M., et al. 1992. TIPS 13, 369.
          Eglen, R., et al. 1998. TiPS 19, 381.
          Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
          Gadie, B., 1984. Br J Pharmacol. 83, 707.
          Fiche technique

          Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

          Revision31-May-2013 JSW
          Synonyms2-(1,4-Benzodioxan-2-yl)-2-imidazoline hydrochloride, RX781094, Idazoxa, α₂-Adrenoceptor Antagonist, Idazoxan Hydrochloride
          DescriptionA non-selective antagonist for ?2-adrenoceptors (pKi = 8.01, 7.43, and 7.7 for ?2A, ?2B, and ?2C receptors respectively) and imidazoline receptors. (pKi = 5.90, 7.22 for I1 and I2, receptors respectively). Widely used in studying functions of the nervous systems, such as learning and memory, decision making, reward, attention, addiction, depression, and schizophrenia related to the adrenergic receptors, and blood pressure regulation, pain modulation, and neuroprotection related to the imidazoline receptors.
          FormWhite powder
          CAS number79944-56-2
          Chemical formulaC₁₁H₁₂N₂O₂ • HCl
          Structure formulaStructure formula
          Purity≥98% by TLC
          SolubilityH₂O (50 mg/ml)
          Storage +15°C to +30°C
          Protect from light
          Do Not Freeze Ok to freeze
          Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C. Stock solutions are stable for up to 3 months at -20°C.
          Toxicity Toxic
          ReferencesHumpston, S., et al. 2013. J. of Psychopharmacology, 27, 213.
          Dabir, l., 1986. J.Pharmacol. 17, 113.
          Michel, M., et al. 1992. TIPS 13, 369.
          Eglen, R., et al. 1998. TiPS 19, 381.
          Doxey, J., et al. 1984. Br J Pharmacol. 1984. 83, 713.
          Gadie, B., 1984. Br J Pharmacol. 83, 707.