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260684 1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem

A specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

Synonyms: DNJ, HCl

Primary Target: Glucosidase 1, glucosidase 2
260684
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₆H₁₃NO₄ · HCl

Products

Catalogue NumberPackaging Qty/Pack
260684-10MG Plastic ampoule 10 mg
260684-1MG Plastic ampoule 1 mg
Description
OverviewA specific glucosidase inhibitor including trimming glucosidases I and II, enzymes that sequentially remove the three glucose residues from precursor Glc3Man9-GlcNAc2 in N-linked glycan biosynthesis.
Catalogue Number260684
Brand Family Calbiochem®
SynonymsDNJ, HCl
References
ReferencesSuh, K., et al. 1992. J. Biol. Chem. 267, 21671.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta 825, 95.
Product Information
CAS number73285-50-4
ATP CompetitiveN
FormCrystalline solid
Hill FormulaC₆H₁₃NO₄ · HCl
Chemical formulaC₆H₁₃NO₄ · HCl
Hygroscopic Hygroscopic
ReversibleN
Structure formula ImageStructure formula Image
Quality LevelMQ100
Applications
Biological Information
Primary TargetGlucosidase 1, glucosidase 2
Purity≥98% by TLC
Physicochemical Information
Cell permeableN
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
R PhraseR: 36/38

Irritating to eyes and skin.
S PhraseS: 26-36

In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Wear suitable protective clothing.
Product Usage Statements
Storage and Shipping Information
Ship Code Ambient Temperature Only
Toxicity Irritant
Storage +2°C to +8°C
Hygroscopic Hygroscopic
Do not freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Packaging Information
Transport Information
Supplemental Information
Specifications

Documentation

1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem SDS

Title

Safety Data Sheet (SDS) 

1-Deoxynojirimycin, Hydrochloride - CAS 73285-50-4 - Calbiochem Certificates of Analysis

TitleLot Number
260684

References

Reference overview
Suh, K., et al. 1992. J. Biol. Chem. 267, 21671.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta 825, 95.
Data Sheet

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision30-April-2008 RFH
SynonymsDNJ, HCl
DescriptionSpecific glucosidase inhibitor, including trimming glucosidases I and II, that sequentially removes the three glucose residues from precursor Glc3Man9GlcNAc2 in N-linked glycan biosynthesis.
FormCrystalline solid
CAS number73285-50-4
Chemical formulaC₆H₁₃NO₄ · HCl
Structure formulaStructure formula
Purity≥98% by TLC
SolubilityH₂O (100 mM)
Storage +2°C to +8°C
Hygroscopic
Do Not Freeze Ok to freeze
Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity Irritant
Merck USA index14, 2905
ReferencesSuh, K., et al. 1992. J. Biol. Chem. 267, 21671.
Fuhrmann, U., et al. 1985. Biochim. Biophys. Acta 825, 95.