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AB19013 Anti-Tenascin Antibody

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50 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
H, ChIHC, IH(P), FUNCRbAffinity PurifiedPolyclonal Antibody
Catalogue NumberAB19013
Brand Family Chemicon®
Trade Name
  • Chemicon
DescriptionAnti-Tenascin Antibody
Product Information
FormatAffinity Purified
  • Embryonic chicken brain
PresentationAffinity Purified using immobilized chicken tenascin. Provided as a liquid in PBS, containing no preservatives.
Quality LevelMQ100
ApplicationAnti-Tenascin Antibody is an antibody against Tenascin for use in IH, IH(P).
Key Applications
  • Immunohistochemistry
  • Immunohistochemistry (Paraffin)
  • Affects Function
Application NotesFunction blocking

Western blot: Antibody recognizes a 220-240kDa band in reduced westerns; antibody reacts best with chicken, followed by human (100X less reactive). Mouse reactivity under reduced conditions is poor.

Immunohistochemistry: frozen and paraffin embedded tissues; citrate treatment useful for paraffin tissues.

Optimal working dilutions must be determined by the end user.
Biological Information
ImmunogenPurified tenascin from embryonic chicken brain.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
SpecificityReactive with tenascin from chicken and human by immunohistochemistry. Under reducing conditions, reactivity to chicken is approximately 100X greater than reactivity with human tenascin. Reactivity with mouse tenascin under reducing conditions is poor, but reacts with mouse in paraffin embedded sections.
Species Reactivity
  • Human
  • Chicken
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • TNC
  • Hexabrachion
  • HXB
  • GMEM
  • TN
  • Neuronectin
  • Tenascin-C
  • MGC167029
  • JI
  • TN-C
  • Cytotactin
Purification MethodImmunoAffinity Purified
UniProt Number
UniProt SummaryFUNCTION: SwissProt: P24821 # Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
SIZE: 2201 amino acids; 240866 Da
SUBUNIT: Homohexamer; disulfide-linked. A homotrimer may be formed in the triple coiled-coil region and may be stabilized by disulfide rings at both ends. Two of such half-hexabrachions may be disulfide linked within the central globule. Interacts with CSPG4.
SUBCELLULAR LOCATION: Secreted, extracellular space, extracellular matrix.
PTM: N-glycosylated (By similarity).
SIMILARITY: SwissProt: P24821 ## Belongs to the tenascin family. & Contains 15 EGF-like domains. & Contains 1 fibrinogen C-terminal domain. & Contains 15 fibronectin type-III domains.
Physicochemical Information
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsMaintain for 2 years at -20°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Packaging Information
Material Size50 µg
Transport Information
Supplemental Information
Global Trade Item Number
Catalogue Number GTIN
AB19013 04053252514791


Anti-Tenascin Antibody SDS


Safety Data Sheet (SDS) 

Anti-Tenascin Antibody Certificates of Analysis

TitleLot Number
RABBIT ANTI-TENASCIN - 3257092 3257092
RABBIT ANTI-TENASCIN - 3284391 3284391
RABBIT ANTI-TENASCIN - 3762609 3762609
RABBIT ANTI-TENASCIN - 4027338 4027338
RABBIT ANTI-TENASCIN - 4119035 4119035
RABBIT ANTI-TENASCIN -2510155 2510155
RABBIT ANTI-TENASCIN -2554841 2554841
RABBIT ANTI-TENASCIN -2586503 2586503
RABBIT ANTI-TENASCIN -2638057 2638057


Reference overviewApplicationSpeciesPub Med ID
Expression of pigment epithelium-derived factor and thrombospondin-1 regulate proliferation and migration of retinal pigment epithelial cells.
Farnoodian, M; Kinter, JB; Yadranji Aghdam, S; Zaitoun, I; Sorenson, CM; Sheibani, N
Physiological reports  3  2015

Show Abstract
25602019 25602019
The impact of flow-induced forces on the morphogenesis of the outflow tract.
Biechler, SV; Junor, L; Evans, AN; Eberth, JF; Price, RL; Potts, JD; Yost, MJ; Goodwin, RL
Frontiers in physiology  5  225  2014

Show Abstract
Immunohistochemistry24987377 24987377
Expression of thrombospondin-1 modulates the angioinflammatory phenotype of choroidal endothelial cells.
Fei, P; Zaitoun, I; Farnoodian, M; Fisk, DL; Wang, S; Sorenson, CM; Sheibani, N
PloS one  9  e116423  2014

Show Abstract
Western Blotting25548916 25548916
Satellite cell activity is differentially affected by contraction mode in human muscle following a work-matched bout of exercise.
Hyldahl, RD; Olson, T; Welling, T; Groscost, L; Parcell, AC
Frontiers in physiology  5  485  2014

Show Abstract
25566087 25566087
Development of a reactive stroma associated with prostatic intraepithelial neoplasia in EAF2 deficient mice.
Pascal, LE; Ai, J; Masoodi, KZ; Wang, Y; Wang, D; Eisermann, K; Rigatti, LH; O'Malley, KJ; Ma, HM; Wang, X; Dar, JA; Parwani, AV; Simons, BW; Ittman, MM; Li, L; Davies, BJ; Wang, Z
PloS one  8  e79542  2013

Show Abstract
24260246 24260246
Cyp1b1 mediates periostin regulation of trabecular meshwork development by suppression of oxidative stress.
Zhao, Y; Wang, S; Sorenson, CM; Teixeira, L; Dubielzig, RR; Peters, DM; Conway, SJ; Jefcoate, CR; Sheibani, N
Molecular and cellular biology  33  4225-40  2013

Show Abstract
Dot BlotMouse23979599 23979599
Aberrant production of extracellular matrix proteins and dysfunction in kidney endothelial cells with a short duration of diabetes.
Grutzmacher, C; Park, S; Zhao, Y; Morrison, ME; Sheibani, N; Sorenson, CM
American journal of physiology. Renal physiology  304  F19-30  2013

Show Abstract
ImmunohistochemistryRat23077100 23077100
Lack of Cyp1b1 promotes the proliferative and migratory phenotype of perivascular supporting cells.
Palenski, TL; Sorenson, CM; Jefcoate, CR; Sheibani, N
Laboratory investigation; a journal of technical methods and pathology  93  646-62  2013

Show Abstract
Immunoblotting (Western)Mouse23568032 23568032
Biochemical and mechanical environment cooperatively regulate skeletal muscle regeneration.
Calve, S; Simon, HG
FASEB journal : official publication of the Federation of American Societies for Experimental Biology  26  2538-45  2012

Show Abstract
Immunohistochemistry22415307 22415307
BIM deficiency differentially impacts the function of kidney endothelial and epithelial cells through modulation of their local microenvironment.
Sheibani, N; Morrison, ME; Gurel, Z; Park, S; Sorenson, CM
American journal of physiology. Renal physiology  302  F809-19  2012

Show Abstract
ImmunofluorescenceMouse22169007 22169007

Data Sheet