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ABT70 Anti-WASH complex subunit 7 (SWIP) Antibody

Detect WASH complex subunit 7 (SWIP) using this Anti-WASH complex subunit 7 (SWIP) Antibody validated for use in IP.

Anti-WASH complex subunit 7 (SWIP) Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
Research Category: Cell Structure Research Sub-Category: Cytoskeletal Signaling Gene Symbol: KIAA10331 UniProt Number: Q2M389
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ABT70
100 µg  
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Key Spec Table

Species ReactivityKey ApplicationsHostFormatAntibody Type
HIPRbPurifiedPolyclonal Antibody
Description
Catalogue NumberABT70
DescriptionAnti-WASH complex subunit 7 (SWIP) Antibody
Alternate Names
  • WASH complex subunit 7
Background InformationWASH complex subunit 7 (SWIP) is a component of the WASH complex belonging to the WASH S7 family. The WASH complex is localized at early endosomal subdomains involved in the activation and recruitment the ARP 2/3 complex in order to stimulate actin polymerization and tubulin interaction. Through its interaction with FAM21, WASH plays a regulatory role in the retromer-mediated trafficking of vesicles. It is also involved in the tubule fission, components required in endosomal sorting processes as transport intermediates.
References
Product Information
FormatPurified
Control
  • HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7
PresentationPurified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality LevelMQ100
Applications
ApplicationDetect WASH complex subunit 7 (SWIP) using this Anti-WASH complex subunit 7 (SWIP) Antibody validated for use in IP.
Key Applications
  • Immunoprecipitation
Biological Information
ImmunogenGST-tagged recombinant protein corresponding to human WASH complex subunit 7.
ConcentrationPlease refer to the Certificate of Analysis for the lot-specific concentration.
HostRabbit
Species Reactivity
  • Human
Antibody TypePolyclonal Antibody
Entrez Gene Number
Gene Symbol
  • KIAA10331
Purification MethodProtein G Purified
UniProt Number
UniProt SummaryFUNCTION: Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting By similarity.

SUBUNIT STRUCTURE: Component of the WASH complex, composed of F-actin-capping protein subunit alpha (CAPZA1, CAPZA2 or CAPZA3), F-actin-capping protein subunit beta (CAPZB), WASH (WASH1, WASH2P, WASH3P, WASH4P, WASH5P or WASH6P), FAM21 (FAM21A, FAM21B or FAM21C), KIAA1033, KIAA0196 and CCDC53.

SEQUENCE SIMILARITIES: Belongs to the WASHS7 family.

SEQUENCE CAUTION: The sequence AAI10851.1 differs from that shown. Reason: Contaminating sequence. Potential poly-A sequence.

The sequence BAA82985.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.
Molecular Weight~135 kDa observed.
IgG heavy chain may be observed at approximately 50 kDa.
Physicochemical Information
Dimensions
Materials Information
Toxicological Information
Safety Information according to GHS
Safety Information
Product Usage Statements
Quality AssuranceEvaluated by Immunoprecipitation/Western Blot Analysis in HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7.

Immunoprecipitation/Western Blot Analysis: 5 µg/mL of this antibody detected WASH complex subunit 7 in 10 µg of HeLa immunoprecipitation with rabbit IgG and Anti-WASH complex subunit 7.
Usage Statement
  • Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Storage and Shipping Information
Storage ConditionsStable for 1 year at 2-8°C from date of receipt.
Packaging Information
Material Size100 µg
Transport Information
Supplemental Information
Specifications
Global Trade Item Number
Catalogue Number GTIN
ABT70 04053252642647

Documentation

Anti-WASH complex subunit 7 (SWIP) Antibody SDS

Title

Safety Data Sheet (SDS) 

Anti-WASH complex subunit 7 (SWIP) Antibody Certificates of Analysis

TitleLot Number
Anti-WASH complex subunit 7 (SWIP) 2476803
Anti-WASH complex subunit 7 (SWIP) - NRG1811385 NRG1811385
Anti-WASH complex subunit 7 (SWIP) - NRG1812597 NRG1812597
Anti-WASH complex subunit 7 (SWIP) - 3237509 3237509
Anti-WASH complex subunit 7 (SWIP) - 3610575 3610575
Anti-WASH complex subunit 7 (SWIP) - NRG1811385 NRG1811385
Anti-WASH complex subunit 7 (SWIP) - NRG1812597 NRG1812597
Anti-WASH complex subunit 7 (SWIP) -2757874 2757874
Anti-WASH complex subunit 7 (SWIP) Polyclonal Antibody 3019778