An invalid quantity was specified. The product quantity has been adjusted.
|341253-5MG||Glass bottle||5 mg|
|Overview||A blood-brain-barrier impermeable p-hydroxyphenylcarbamate compound that acts as a potent and irreversible inhibitor of FAAH activity (IC50 = 26.8 nM rat brain) with excellent selectivity over monoacylglycerol lipases (IC50 > 100 µM). Shown to rapidly block mouse liver FAAH activity over brain (ED50 = 0.2 mg/kg vs. 40 mg/kg, s.c.), elevate anandamide and palmitoylethanolamide levels in peripheral tissues (1 mg/kg, i.p.) and exert antinociceptive action. The CNS-penetrant FAAH Inhibitor II, URB597 is also available (Cat. No. 341249).|
|Synonyms||Cyclohexylcarbamic acid-carbamoylhydroxybiphenyl–3–yl)ester, Cyclohexylcarbamic acid-(3ʹ–carbamoyl–6–hydroxybiphenyl–3–yl)ester, Fatty Acid Amide Hydrolase Inhibitor III, URB937|
|References||Clapper, J.R., et al. 2010. Nat. Neurosci. 13, 1265.|
|Structure formula Image|
|Purity||≥95% by HPLC|
|Safety Information according to GHS|
|Product Usage Statements|
|Packaged under inert gas||Packaged under inert gas|
FAAH Inhibitor III, URB937 - Calbiochem SDS
|Clapper, J.R., et al. 2010. Nat. Neurosci. 13, 1265.|
Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.