568500
SQ 22536
≥98% (HPLC), adenylate cyclase inhibitor, solid
동의어(들):
SQ 22536, 9-(Tetrahydro-2ʹ-furyl)adenine
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크기 선택
보기 변경
제품정보 (DICE 배송 시 비용 별도)
실험식(Hill 표기법):
C9H11N5O
CAS 번호:
Molecular Weight:
205.22
UNSPSC Code:
12352200
NACRES:
NA.77
MDL number:
Assay:
≥98% (HPLC)
Form:
solid
Storage condition:
OK to freeze
제품 이름
SQ 22536, Cell-permeable adenylate cyclase inhibitor.
Quality Segment
assay
≥98% (HPLC)
form
solid
manufacturer/tradename
Calbiochem®
storage condition
OK to freeze
color
off-white
solubility
DMSO: 25 mg/mL, water: 5 mg/mL
shipped in
ambient
storage temp.
2-8°C
SMILES string
[n]2(c3ncnc(c3nc2)N)C1OCCC1
InChI
1S/C9H11N5O/c10-8-7-9(12-4-11-8)14(5-13-7)6-2-1-3-15-6/h4-6H,1-3H2,(H2,10,11,12)
InChI key
UKHMZCMKHPHFOT-UHFFFAOYSA-N
General description
Cell-permeable adenylate cyclase inhibitor. Blocks PTH-stimulation of adenylate cyclase (IC50 = 200 µM). Reduces PGE2-induced inhibition of O2·– production.
Biochem/physiol Actions
Cell permeable: yes
Primary Target
adenylate cyclase
adenylate cyclase
Product does not compete with ATP.
Reversible: no
Target IC50: 200 µM against adenylate cyclase
Preparation Note
Following reconstitution, store in the refrigerator (4°C). Stock solutions are stable for up to 2 weeks at 4°C.
Other Notes
Talpain, E., et al. 1995. Br. J. Pharmacol. 114, 1459.
Tamaoki, J., et al. 1993. Prostaglandins45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
Tamaoki, J., et al. 1993. Prostaglandins45, 363.
Fabbri, E., et al. 1991. J. Enzyme Inhib.5, 87.
Goldsmith, B.A. and Abrams, T.W. 1991. Proc. Natl. Acad. Sci. USA 88, 9021.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Irritant (B)
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저장 등급
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
시험 성적서(COA)
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