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Merck

07-862

Sigma-Aldrich

Anti-phospho-PDGFRα (Tyr754) Antibody

Upstate®, from rabbit

Synonym(s):

CD140A, MGC74795, PDGFR2, platelet-derived growth factor receptor, alpha

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About This Item

UNSPSC Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

biological source

rabbit

Quality Level

100

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

purified by

affinity chromatography

species reactivity

mouse, human

manufacturer/tradename

Upstate®

technique(s)

western blot: suitable

isotype

IgG

NCBI accession no.

NM_006206.3

UniProt accession no.

P16234
Q9UD28

shipped in

dry ice

target post-translational modification

phosphorylation (pTyr754)

Gene Information

human ... PDGFRA(5156)

General description

170-185 kDA
The previously assigned protein identifier Q9UD28 has been merged into P16234. Full details can be found on the UniProt database.

Immunogen

Peptide corresponding to amino acid region encompassing the human phospho-PDGFRα (Tyr754).

Application

Research Category
Signaling
Research Sub Category
Growth Factors & Receptors
This Anti-phospho-PDGFRα (Tyr754) Antibody is validated for use in WB for the detection of phospho-PDGFRα (Tyr754).

Biochem/physiol Actions

Human and Mouse PDGFRα that is phosphorylated on Tyrosine 754 and 762, respectively. Rat is predicted to react based on sequence homology.
Predicted to cross-react with rat based on 100% sequence similarity, but has not been tested.

Physical form

100 μL of affinity purified rabbit polyclonal IgG in buffer (PBS (without Mg2+ and Ca2+), pH 7.4 containing 1.0 mg/mL BSA (IgG, protease free) and 0.05% sodium azide).
Affinity purified

Preparation Note

2 years at -80°C.
Upon first thaw, and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -80°C. Avoid repeated freeze/ thaw cycles, which may damage IgG and affect product performance.

Legal Information

UPSTATE is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 2

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Regulation of platelet-derived growth factor receptor function by integrin-associated cell surface transglutaminase.
Zemskov, EA; Loukinova, E; Mikhailenko, I; Coleman, RA; Strickland, DK; Belkin, AM
The Journal of Biological Chemistry null

Global Trade Item Number

SKUGTIN
07-86204053252474422

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