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218746 Caspase-1 Inhibitor VI - Calbiochem

218746
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Overview

Replacement Information

Key Spec Table

Empirical Formula
C₃₁H₃₉FN₄O₉

Pricing & Availability

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218746-250UGCN
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      Plastic ampoule 250 μg
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      Description
      OverviewA potent, cell-permeable, and irreversible inhibitor of caspase-1 (ICE), caspase-4, and caspase-5.
      Catalogue Number218746
      Brand Family Calbiochem®
      SynonymsZ-YVAD-FMK
      References
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.
      Product Information
      ATP CompetitiveN
      FormWhite powder
      Hill FormulaC₃₁H₃₉FN₄O₉
      Chemical formulaC₃₁H₃₉FN₄O₉
      ReversibleN
      Structure formula ImageStructure formula Image
      Quality LevelMQ100
      Applications
      Biological Information
      Primary Targetcaspase-1
      Purity≥95% by HPLC or TLC
      Physicochemical Information
      Cell permeableY
      Peptide SequenceZ-Tyr-Val-Ala-Asp(OMe)-CH₂F*
      Dimensions
      Materials Information
      Toxicological Information
      Safety Information according to GHS
      Safety Information
      Product Usage Statements
      Storage and Shipping Information
      Ship Code Ambient Temperature Only
      Toxicity Standard Handling
      Storage -20°C
      Protect from Moisture Protect from moisture
      Do not freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
      Packaging Information
      Transport Information
      Supplemental Information
      Specifications

      Documentation

      Caspase-1 Inhibitor VI - Calbiochem SDS

      Title

      Safety Data Sheet (SDS) 

      Caspase-1 Inhibitor VI - Calbiochem Certificates of Analysis

      TitleLot Number
      218746

      References

      Reference overview
      Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.

      Brochure

      Title
      Caspases and other Apoptosis Related Tools Brochure
      Data Sheet

      Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

      Revision06-February-2018 JSW
      SynonymsZ-YVAD-FMK
      DescriptionA potent, cell-permeable and irreversible inhibitor of caspase-1 (ICE).
      FormWhite powder
      Chemical formulaC₃₁H₃₉FN₄O₉
      Peptide SequenceZ-Tyr-Val-Ala-Asp(OMe)-CH₂F*
      Structure formulaStructure formula
      Purity≥95% by HPLC or TLC
      SolubilityDMSO (5 mg/ml)
      Storage -20°C
      Protect from moisture
      Do Not Freeze Ok to freeze
      Special InstructionsFollowing reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 4 months at -20°C.
      Toxicity Standard Handling
      ReferencesThornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312.
      Eldadah, B.A., et al. 1997. J. Neurosci. 17, 6105.

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      Categories

      Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Apoptosis/Necrosis Inhibitors > Caspase Inhibitors