Operation, Optimization and
Scale-up of Clarification
One Day Course
Course Description
Using a combination of theory and hands-on instruction, participants will learn the basic operational step sequence, key parameters and techniques involved in the development and optimization of clarification processes using depth filtration. The course covers the central elements of depth filtration including equipment components, flushing, equilibration, filtration and product recovery.
Course ID: TRCLARIF
Learning Goals
- Understand the terminology and basic concepts of Clarification.
- Define and optimize suitable clarification strategies.
- Perform filter installation and disassembly.
- Implement best practice procedures for depth filtration operation.
- Perform standard clarification operations including pre-flushing and post-flushing for recovery.
- Identification ways to improve your existing process.
What will you receive?
- A copy of the principle course materials
- Protocol and results of laboratory sessions
- A certificate of attendance
Who should attend?
This course is designed for R&D scientists and pilot and production departments who have responsibility for developing and implementing clarification processes in the pharmaceutical and biopharmaceutical industry.
Course Schedule and Program
- Course Introduction
- Introduction to Depth Filtration (Fundamentals and Processing Basics)
- Practical Session #1 Sizing test by constant flow
(Set up, Flush, and Equilibration Steps) - Practical Session #2 Sizing test by constant flow
(Filtration and Product Recovery Steps) - Clarification operation and Scale-up
- Practical Session #3 Installation and filtration in Pilot scale
- Interpreting the test results from practical Session
- Workshop
- Written Assessment
- Conclusion
Enrollment is Limited
Due to the hands-on nature of this course, enrollment is limited. We recommend early booking to ensure a place.
Price
Please contact your local representative or send an email to ilearn@merckgroup.com for a quote.