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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

MABS518 Sigma-AldrichAnti-CBS Antibody, clone 9F3.2

Anti-CBS Antibody, clone 9F3.2 is an antibody against CBS for use in Western Blotting, Immunohistochemistry (Paraffin).

Anti-CBS Antibody, clone 9F3.2 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
小册子
技术信息
Posters

Research Category: Signaling Research Sub-Category: Signaling Neuroscience Gene Symbol: CBS UniProt Number: P35520

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB, IH(P)	M	Purified	Monoclonal Antibody

Description
Catalogue Number	MABS518
Description	Anti-CBS Antibody, clone 9F3.2
Alternate Names	Cystathionine beta-synthase CBS Beta-thionase Serine sulfhydrase
Background Information	Cystathionine beta-synthase (EC 4.2.1.22; UniProt P35520; also known as beta-thionase, Methylcysteine synthase, Serine sulfhydrase) is encoded by the CBS (also known as HIP4) gene (Gene ID 875) in human. Cystathionine beta-synthase catalyzes the trans-sulfuration of homocysteine and serine to form the cysteine precursor cystathionine in the folate pathway. Cysteine is an essential substrate for the biosynthesis of glutathione, a major endogenous antioxidant. CBS deficiency results in altered sulfur metabolism and homocystinuria characterized by increased urinary homocystine and methionine. The clinical features of untreated homocystinuria due to CBS deficiency include myopia, ectopia lentis, mental retardation, skeletal anomalies resembling Marfan syndrome, and thromboembolic events.

References

Product Information
Format	Purified
Presentation	Purified mouse monoclonal IgG2aκ antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-CBS Antibody, clone 9F3.2 is an antibody against CBS for use in Western Blotting, Immunohistochemistry (Paraffin).
Key Applications	Western Blotting Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry Analysis: A 1:1,000 dilution from a representative lot detected CBS in human liver and human pancreas tissue.

Biological Information
Immunogen	Recombinant protein corresponding to the N-terminal of human CBS.
Epitope	N-terminal
Clone	9F3.2
Concentration	Please refer to lot specific datasheet.
Host	Mouse
Specificity	Expected to react with both the Major (isoform 1) and the Minor (isoform 2) spliced variant.
Isotype	IgG2aκ
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Entrez Gene Number	NP_001171479
Gene Symbol	CBS
Purification Method	Protein G Purified
UniProt Number	P35520
Molecular Weight	~61 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in Raji cell lysate. Western Blotting Analysis: 0.5 µg/mL of this antibody detected CBS in 10 µg of Raji cell lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 μg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABS518	04055977182828

Documentation

Anti-CBS Antibody, clone 9F3.2 MSDS

职位
物料安全数据表 (MSDS)

Anti-CBS Antibody, clone 9F3.2 分析证书

标题	批号
Anti-CBS, clone 9F3.2 - 3384388	3384388
Anti-CBS, clone 9F3.2 - 4113023	4113023
Anti-CBS, clone 9F3.2 -Q2589906	Q2589906

小册子

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技术信息

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White Paper: Further considerations of antibody validation and usage.

海报

标题
Post-Translational Modifications

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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