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MABN683 Sigma-AldrichAnti-ETV5 Antibody, clone 3H3

Anti-ETV5 Antibody, clone 3H3 is a highly specific mouse monoclonal antibody & that targets Ets & has been tested in western blotting.

Anti-ETV5 Antibody, clone 3H3 MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: ERM, ETV5 UniProt Number: P41161

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H	WB	M	Ascites	Monoclonal Antibody

Description
Catalogue Number	MABN683
Description	Anti-ETV5 Antibody, clone 3H3
Alternate Names	ETS translocation variant 5 Ets-related protein ERM ETV5
Background Information	ETS family members play an important role in mammalian development and have been implicated in the regulation of gene expression during a variety of biologic processes including cell growth and differentiation. Defects or deficiencies, as well as overexpression of ETS family members can have major developmental effects as well as aid in tumor development. ETS translocation variant 5 protein (ETV5) also known as ETS-related protein ERM is a nuclear localized protein that binds to DNA sequences containing the consensus nucleotide core sequence of GGAA and is a member of the very large ETS transcription factor family. Early experiments in worms suggested that ETV5 might play a role in the development of the dopaminergic nervous system; however that has not proved to be the case in mammals. However, more recent research has indicated ETV5 playing an important role in the development of reproduction and in the development of ovarian cancer. ETV5 controls the expression of critical prostaglandins needed for ovarian development and ETV5 deficient mice show complex infertility phenotypes both in males and females. In males, the infertility phenotype exhibited by ETV5 deficiency is sexually dimorphic, and it involves both somatic cells and germ cells. In Etv5-/- female mice, the problem is more complicated by hormonal involvement and results in more a complex phenotype. EMD-Millipore’s Anti-ETV5 mouse monoclonal antibody has been tested in western blot against Jurkat, NIH3T3 and MCF-7 cell lysates.

References

Product Information
Format	Ascites
Control	Jurkat, NIH/3T3 and MCF-7 cell lysates
Presentation	Mouse monoclonal IgG1 ascitic fluid containing up to 0.1% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-ETV5 Antibody, clone 3H3 is a highly specific mouse monoclonal antibody & that targets Ets & has been tested in western blotting.
Key Applications	Western Blotting

Biological Information
Immunogen	Purified recombinant fragment of human ETV5 expressed in E. Coli.
Clone	3H3
Host	Mouse
Isotype	IgG1
Species Reactivity	Human
Antibody Type	Monoclonal Antibody
Gene Symbol	ERM ETV5
Purification Method	Unpurified
UniProt Number	P41161
Molecular Weight	~58 kDa observed. Uncharacterized bands may appear in some lysate(s).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in Jurkat, NIH/3T3 and MCF-7 cell lysates. Western Blotting Analysis: A 1:500-2,000 dilution of this antibody detected ETV5 in Jurkat, NIH/3T3 and MCF-7 cell lysates. Optimal working dilutions must be determined by end user.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
MABN683	04053252917493

Documentation

Anti-ETV5 Antibody, clone 3H3 MSDS

职位
物料安全数据表 (MSDS)

Anti-ETV5 Antibody, clone 3H3 分析证书

标题	批号
Anti-ETV5, clone 3H3 - VP1401286	VP1401286
Anti-ETV5, clone 3H3 - QVP1305163	QVP1305163
Anti-ETV5, clone 3H3 -VP1502260	VP1502260
Anti-ETV5, clone 3H3 -VP1602242	VP1602242
Anti-ETV5, clone 3H3 -VP1607212	VP1607212
Anti-ETV5, clone 3H3 Monoclonal Antibody	VP1804272
Anti-ETV5, clone 3H3 Monoclonal Antibody	VP1707284
Anti-ETV5, clone 3H3 Monoclonal Antibody	VP1810191

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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