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AB951-I Sigma-AldrichAnti-Neuron Specific Enolase Antibody

Anti-Neuron Specific Enolase Antibody is a highly specific rabbit polyclonal antibody, that targets Neuron-Specific Enolase & has been tested in western blotting & IHC (Paraffin).

Anti-Neuron Specific Enolase Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书

Research Category: Neuroscience Research Sub-Category: Developmental Neuroscience Gene Symbol: ENO2 UniProt Number: P09104

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, R, M	WB, IH(P)	Rb	Purified	Polyclonal Antibody

Description
Catalogue Number	AB951-I
Replaces	AB951
Description	Anti-Neuron Specific Enolase Antibody
Alternate Names	Gamma-enolase 2-phospho-D-glycerate hydro-lyase Enolase 2 Neural enolase Neuron-specific enolase NSE
Background Information	The glycolytic enzyme enolase (2-phospho-D-glycerate hydrolase, E.C. 4.2.1.11) is composed of two subunits and exists in three molecular forms in human brain: non-neuronal enolase (NNE; alpha, alpha'-enolase), neuron-specific enolase (NSE; gamma,gamma'-enolase, also known as 14-3-2 protein and NSP) and the short-lived heterodimer alpha, gamma'-enolase. The neuron specific form is a highly acidic homodimeric protin of 78kDa, which has been found in central and peripheral nervous elements and also in many neuroendocrine cells and derivative tumors. NSE is regarded as the best described serum marker for small cell lung cancer. In addition, the measurement of NSE levels in both serum and cerebrospinal fluid following cerebral ischaemia and traumatic head injury provides a reliable laboratory indicator of the degree of brain cell damage and may allow early prediction of prognostic outcome.

References

Product Information
Format	Purified
HS Code	3002 15 90
Control	Rat brain tissue lysate
Presentation	Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Anti-Neuron Specific Enolase Antibody is a highly specific rabbit polyclonal antibody, that targets Neuron-Specific Enolase & has been tested in western blotting & IHC (Paraffin).
Key Applications	Western Blotting Immunohistochemistry (Paraffin)
Application Notes	Immunohistochemistry Analysis: A 1:100 dilution from a representative lot detected in Neuron Specific Enolase in human thalamus tissue and glioma sections.

Biological Information
Immunogen	KLH-conjugated linear peptide corresponding to the near N-terminus of human Neuron Specific Enolase.
Epitope	Near N-terminus
Concentration	Please refer to the Certificate of Analysis for the lot-specific concentration.
Host	Rabbit
Specificity	This antibody recognizes a region near the N-terminus of Neuron Specific Enolase.
Species Reactivity	Human Rat Mouse
Species Reactivity Note	Demonstrated to react with Human, Rat, and Mouse. Predicted to react with Bovine based on 100% sequence homology.
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NP_001966
Gene Symbol	ENO2
Purification Method	Protein A Purfied
UniProt Number	P09104
Molecular Weight	~47 kDa observed. Cat. No. AB951, Anti-Neuron Specific Enolase detects Alpha Enolase (ENO1) at ~39kDa. However, Neuron Specific Enolase has been observed at ~48 kDa (Braus, B., K., et al (2008). Vet Immunol Immunopathol 124(1-2):177-183.; Feo, S., et al. (2000). FEBS Lett. 473(1):47-52.).

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in rat brain tissue lysate. Western Blotting Analysis: 1 µg/mL of this antibody detected Neuron Specific Enolase in 10 µg of rat brain tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µg

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
AB951-I	04053252916618

Documentation

Anti-Neuron Specific Enolase Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-Neuron Specific Enolase Antibody 分析证书

标题	批号
Anti-Neuron Specific Enolase	3077906
Anti-Neuron Specific Enolase - 2564451	2564451
Anti-Neuron Specific Enolase - 3022879	3022879
Anti-Neuron Specific Enolase - 3236379	3236379
Anti-Neuron Specific Enolase - 3547803	3547803
Anti-Neuron Specific Enolase - 3764443	3764443
Anti-Neuron Specific Enolase - 3853789	3853789
Anti-Neuron Specific Enolase - 3944146	3944146
Anti-Neuron Specific Enolase - Q2218163	Q2218163
Anti-Neuron Specific Enolase -2576418	2576418

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种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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