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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

AB9094-I Sigma-AldrichAnti-Sodium Pump Subunit alpha-2 Antibody

Detect Sodium Pump Subunit alpha-2 using this Anti-Sodium Pump Subunit alpha-2 Antibody validated for use in Western Blotting, Immunohistochemistry (Paraffin) and Immunoprecipitation.

Anti-Sodium Pump Subunit alpha-2 Antibody MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
技术信息

Research Category: Neuroscience Research Sub-Category: Developmental Signaling Gene Symbol: Atp1a2 UniProt Number: P06686

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概述

Replacement Information

特卖

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重要规格表

Species Reactivity	Key Applications	Host	Format	Antibody Type
H, M, R	WB, IH(P), IP	Rb	Affinity Purified	Polyclonal Antibody

Description
Catalogue Number	AB9094-I
Replaces	AB9094
Description	Anti-Sodium Pump Subunit alpha-2 Antibody
Alternate Names	Sodium/potassium-transporting ATPase subunit alpha-2 Na(+)/K(+) ATPase alpha-2 subunit Na(+)/K(+) ATPase alpha(+) subunit Sodium pump subunit alpha-2 Sodium Pump Subunit alpha-2 Anti-Sodium Pump (Na+ pump (Na+-K+-ATPase)) α 2 Isoform Sodium/potassium-transporting ATPase subunit alpha-2 ATP1A2
Background Information	Sodium/potassium-transporting ATPase subunit alpha-2 (EC 3.6.3.9; UniProt P06686; also known as Na+/K+ -ATPase alpha 2 subunit, Na(+)/K(+) ATPase alpha(+) subunit, Sodium pump subunit alpha-2) is encoded by the Atp1a2 (also known as RATATPA2) gene (Gene ID 24212) in rat. Mammalian Na+/K+ ATPase is a heteromultimeric complex composed of alpha, beta, and gamma subunits. The alpha subunit catalyzes the hydrolysis of ATP coupled with the exchange of Na+ and K+ across the plasma membrane. The alpha subunit contains ten transmembrane domains with both its N- and C-termini in the cytoplasm. More than 50 mutations have been identified affecting the human ATP1A2 and ATP1A3 genes that are known to cause rapid-onset Dystonia Parkinsonism, familial hemiplegic migraine, alternating hemiplegia of childhood, and variants of familial hemiplegic migraine with neurological complications including seizures and various mood disorders.

References

Product Information
Format	Affinity Purified
Presentation	Purified rabbit polyclonal antibody in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.
Quality Level	MQ100

Applications
Application	Detect Sodium Pump Subunit alpha-2 using this Anti-Sodium Pump Subunit alpha-2 Antibody validated for use in Western Blotting, Immunohistochemistry (Paraffin) and Immunoprecipitation.
Key Applications	Western Blotting Immunohistochemistry (Paraffin) Immunoprecipitation
Application Notes	Immunohistochemistry Analysis (IHC): A representative lot detected Sodium Pump Subunit alpha-2 in human (1:1,000) and rat (1:250) cerebellum tissue sections. Immunoprecipitation Analysis (IP): 10 ug from a representative lot immunoprecipitated Sodium Pump Subunit alpha-2 in 500 µg of rat brain tissue lysate.

Biological Information
Immunogen	KLH-conjugated linear peptide corresponding to the second cytoplasmic domain of rat Sodium Pump Subunit alpha-2.
Epitope	Second cytoplasmic domain
Concentration	Please refer to lot specific datasheet.
Host	Rabbit
Specificity	Reacts with Sodium Pump (Na+ pump (Na+-K+-ATPase)) alpha 2 isoform. The antibody does not cross react with other Na+-K+-ATPase alpha isoforms.
Species Reactivity	Human Mouse Rat
Species Reactivity Note	Human, Mouse, Rat. Predicted to react with Bovine, Porcine based on 100% sequence homology.
Antibody Type	Polyclonal Antibody
Entrez Gene Number	NP_036637
Gene Symbol	Atp1a2
Purification Method	Affinity Purfied
UniProt Number	P06686
Molecular Weight	~100 kDa observed

Physicochemical Information

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements
Quality Assurance	Evaluated by Western Blotting in rat brain tissue lysate. Western Blotting Analysis: A 1:4,000 dilution of this antibody detected Sodium Pump Subunit alpha-2 in 10 µg of rat brain tissue lysate.
Usage Statement	Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage and Shipping Information
Storage Conditions	Stable for 1 year at 2-8°C from date of receipt.

Packaging Information
Material Size	100 µL

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
AB9094-I	04055977173390

Documentation

Anti-Sodium Pump Subunit alpha-2 Antibody MSDS

职位
物料安全数据表 (MSDS)

Anti-Sodium Pump Subunit alpha-2 Antibody 分析证书

标题	批号
Anti-Sodium Pump Subunit alpha-2 - 3228351	3228351
Anti-Sodium Pump Subunit alpha-2 - 3280268	3280268
Anti-Sodium Pump Subunit alpha-2 - 3448549	3448549
Anti-Sodium Pump Subunit alpha-2 - 3700881	3700881
Anti-Sodium Pump Subunit alpha-2 - 3907844	3907844
Anti-Sodium Pump Subunit alpha-2 - 4166974	4166974
Anti-Sodium Pump Subunit alpha-2 - 4247790	4247790
Anti-Sodium Pump Subunit alpha-2 -2796794	2796794
Anti-Sodium Pump Subunit alpha-2 -2855648	2855648
Anti-Sodium Pump Subunit alpha-2 -Q2574768	Q2574768

技术信息

标题
Characterization of Estrogen Receptor α Phosphorylation Sites in Breast Cancer Tissue Using the SNAP i.d® 2.0 System
White Paper: Further considerations of antibody validation and usage.

种类

Life Science Research > Antibodies and Assays > Primary Antibodies

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