218759 Sigma-AldrichCaspase-8 Inhibitor II - Calbiochem
Caspase-8 Inhibitor II, CAS 210344-98-2, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B.
More>> Caspase-8 Inhibitor II, CAS 210344-98-2, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B. Less<<Caspase-8 Inhibitor II - Calbiochem MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: Z-IE(OMe)TD(OMe)-FMK, Granzyme B Inhibitor III
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概述
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重要规格表
| Empirical Formula |
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| C₃₀H₄₃FN₄O₁₁ |
| Description | |
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| Overview | A potent, cell-permeable, and irreversible inhibitor of caspase-8 and granzyme B. Effectively inhibits influenza virus-induced apoptosis in HeLa cells. Also inhibits granzyme B. When using with purified native or recombinant enzyme, pretreatment with an esterase is required. A 5 mM (250 µg/76 µl) solution of Z-IETD-FMK (Cat. No. 218840) in DMSO is also available. |
| Catalogue Number | 218759 |
| Brand Family | Calbiochem® |
| Synonyms | Z-IE(OMe)TD(OMe)-FMK, Granzyme B Inhibitor III |
| Product Information | |
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| ATP Competitive | N |
| Form | White to yellow powder |
| Hill Formula | C₃₀H₄₃FN₄O₁₁ |
| Chemical formula | C₃₀H₄₃FN₄O₁₁ |
| Reversible | N |
| Quality Level | MQ100 |
| Applications | |
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| Application | Caspase-8 Inhibitor II, CAS 210344-98-2, is a potent, cell-permeable, irreversible inhibitor of caspase-8 and granzyme B. |
| Biological Information | |
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| Primary Target | caspase-8 |
| Purity | ≥98% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
| Peptide Sequence | Z-Ile-Glu(OMe)-Thr-Asp(OMe)-CH₂F* |
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| Specifications |
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| 产品目录编号 | GTIN |
| 218759 | 0 |
Documentation
Caspase-8 Inhibitor II - Calbiochem MSDS
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Caspase-8 Inhibitor II - Calbiochem 分析证书
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| 218759 |
参考
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| Takizawa, T., et al. 1999. Microbiol. Immunol. 43, 245. Martin, D.A., et al. 1998. J. Biol. Chem. 273, 4345. Sweeney, E.A., et al. 1998. FEBS Lett. 425, 61. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. |
小册子
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| Caspases and other Apoptosis Related Tools Brochure |
引用
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Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.
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