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218765 Sigma-AldrichCaspase-9 Substrate I, Fluorogenic - CAS 210345-03-2 - Calbiochem

A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6).

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
小册子
Data Sheet

同义词: Ac-LEHD-AFC

Recommended Products

概述

Replacement Information

Description
Overview	A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). May also act as a substrate for caspase-4 and caspase-5. Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore.
Catalogue Number	218765
Brand Family	Calbiochem®
Synonyms	Ac-LEHD-AFC

References
References	Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

Product Information
CAS number	210345-03-2
ATP Competitive	N
Form	White solid
Formulation	Supplied as a trifluoroacetate salt.
Hill Formula	C₃₃H₃₈F₃N₇O₁₁
Chemical formula	C₃₃H₃₈F₃N₇O₁₁
Reversible	N
Quality Level	MQ100

Applications

Biological Information
Primary Target	A fluorogenic substrate for caspase-9
Purity	≥95% by HPLC

Physicochemical Information
Cell permeable	N
Emission max.
Excitation max.
Peptide Sequence	Ac-Leu-Glu-His-Asp-AFC

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Ambient Temperature Only
Toxicity	Standard Handling
Storage	-20°C
Protect from Light	Protect from light
Protect from Moisture	Protect from moisture
Do not freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
218765	0

Documentation

Caspase-9 Substrate I, Fluorogenic - CAS 210345-03-2 - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

Caspase-9 Substrate I, Fluorogenic - CAS 210345-03-2 - Calbiochem 分析证书

标题	批号
218765	输入批号

参考

参考信息概述
Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

小册子

标题
Caspases and other Apoptosis Related Tools Brochure

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	04-June-2008 RFH
Synonyms	Ac-LEHD-AFC
Description	A fluorogenic substrate for caspase-9 (ICE-LAP6, Mch6). Reaction can be monitored visually or quantitatively by a blue to green shift in fluorescence upon cleavage of the AFC fluorophore (excitation maximum: ~400 nm; emission maximum: ~505 nm).
Form	White solid
Formulation	Supplied as a trifluoroacetate salt.
CAS number	210345-03-2
Chemical formula	C₃₃H₃₈F₃N₇O₁₁
Peptide Sequence	Ac-Leu-Glu-His-Asp-AFC
Purity	≥95% by HPLC
Solubility	DMSO (5 mg/ml)
Storage	Protect from moisture Protect from light -20°C
Do Not Freeze	Ok to freeze
Special Instructions	Following reconstitution aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Toxicity	Standard Handling
References	Ito, A., et al. 1999. Biochim. Biophys. Acta 1452, 263. Thornberry, N.A., and Lazebnik, Y. 1998. Science 281, 1312. Thornberry, N.A., et al. 1997. J. Biol. Chem. 272, 17907.

种类

Life Science Research > Proteins and Enzymes > Substrate & Control Proteins > Protease Substrates

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