219478 Sigma-AldrichCdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem
The Cdk4 Inhibitor III, also referenced under CAS 265312-55-8, controls the biological activity of Cdk4. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications.
More>> The Cdk4 Inhibitor III, also referenced under CAS 265312-55-8, controls the biological activity of Cdk4. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Less<<MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.
同义词: 5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole, Ryuvidine
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概述
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重要规格表
| CAS # | Empirical Formula |
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| 265312-55-8 | C₁₅H₁₂N₂O₂S |
价格及供货情况
| 产品目录编号 | 库存情况 | 包装 | 数量 / 包装 | 价格 | 数量 | |
|---|---|---|---|---|---|---|
| 219478-5MGCN |
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塑胶安瓿;塑胶针药瓶 | 5 mg |
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| Description | |
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| Overview | A cell-permeable dioxobenzothiazole compound that acts a selective Cdk4 inhibitor (IC50 = 6.0 µM for Cdk4/D1 and > 200 µM for Cdk2/A). Exhibit better cytotoxic potential against cancer cells (IC50 = 0.61, 1.08, 0.30, and 1.21 µg/ml against A 549, Col 1, HL-60, and HepG2 tumor cells, respectively) than Cisplatin (Cat. No. 232120). |
| Catalogue Number | 219478 |
| Brand Family | Calbiochem® |
| Synonyms | 5-(N-(4-Methylphenyl)amino)-2-methyl-4,7-dioxobenzothiazole, Ryuvidine |
| References | |
|---|---|
| References | Ryu, C.K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 461. |
| Product Information | |
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| CAS number | 265312-55-8 |
| ATP Competitive | N |
| Form | Black-purple solid |
| Hill Formula | C₁₅H₁₂N₂O₂S |
| Chemical formula | C₁₅H₁₂N₂O₂S |
| Reversible | N |
| Structure formula Image | |
| Quality Level | MQ100 |
| Applications |
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| Biological Information | |
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| Primary Target | Cdk4 |
| Primary Target IC<sub>50</sub> | 6.0 µM for Cdk4/D1 and > 200 µM for Cdk2/A |
| Purity | ≥90% by HPLC |
| Physicochemical Information | |
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| Cell permeable | Y |
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| Toxicological Information |
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| Safety Information according to GHS |
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| Safety Information |
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| Product Usage Statements |
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| Packaging Information | |
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| Packaged under inert gas | Packaged under inert gas |
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| Specifications |
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| Global Trade Item Number | |
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| 产品目录编号 | GTIN |
| 219478-5MGCN | 04055977218558 |
Documentation
Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem MSDS
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Cdk4 Inhibitor III - CAS 265312-55-8 - Calbiochem 分析证书
| 标题 | 批号 |
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| 219478 |
参考
| 参考信息概述 |
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| Ryu, C.K., et al. 2000. Bioorg. Med. Chem. Lett. 10, 461. |