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			96-Well Plate

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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

233552 Sigma-AldrichCobra Venom Factor, Naja naja kaouthia

Cobra Venom Factor, Naja naja kaouthia, is a native cobra venom factor. Glycoprotein composed of three non-identical disulfide-bonded subunits of 68, 48, and 30 kDa.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Cobra Venom Anticomplementary Protein

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概述

Replacement Information

价格及供货情况

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Description
Overview	Native cobra venom factor from Naja naja kaouthia. Glycoprotein composed of three non-identical disulfide-bonded subunits with M.W. of 68 kDa (α), 48 kDa (β), and 30 kDa (γ). Cobra venom factor (CVF) is a structural and functional analog of cobra, as well as mammalian C3. Thus, in the presence of Factor B, Factor D, and Mg²⁺, CVF can form a stable CVF,Bb complex that is a C3/C5 convertase enzyme; however, the CVF,Bb complex is not susceptible to regulation by Factors H and I. Four to six µg of purified CVF are equal to 1.0 unit of functional activity as measured by the method of Cochrane, et al.
Catalogue Number	233552
Brand Family	Calbiochem®
Synonyms	Cobra Venom Anticomplementary Protein

References
References	Bogers, W.M., et al. 1993. Eur. J. Immunol. 23, 433. Fritzinger, D.C., et al. 1992. J. Immunol. 149, 3554. Muller, B. and Muller-Ruchholtz, W. 1987. Leuk. Res. 11, 461. Vogel, C.W. and Muller-Eberhard, H.J. 1984. J. Immunol. Methods 73, 203. Cochrane, C.G., et al. 1970. J. Immunol. 105, 55. Ballows, M. and Cochrane, C.G. 1969. J. Immunol. 103, 944.

Product Information
Activity	≥250 units/ml
Declaration	Not available for sale outside the United States.
Form	Liquid
Formulation	In PBS, pH 7.2.
Quality Level	MQ100

Applications

Biological Information
Purity	≥95% by SDS-PAGE
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information
Contaminants	Phospholipase: none detected

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information
R Phrase	R: 20/21/22 Harmful by inhalation, in contact with skin and if swallowed.
S Phrase	S: 36 Wear suitable protective clothing.

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Harmful
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
233552-1MGCN	04055977217896

Documentation

Cobra Venom Factor, Naja naja kaouthia MSDS

职位
物料安全数据表 (MSDS)

Cobra Venom Factor, Naja naja kaouthia 分析证书

标题	批号
233552	输入批号

参考

参考信息概述
Bogers, W.M., et al. 1993. Eur. J. Immunol. 23, 433. Fritzinger, D.C., et al. 1992. J. Immunol. 149, 3554. Muller, B. and Muller-Ruchholtz, W. 1987. Leuk. Res. 11, 461. Vogel, C.W. and Muller-Eberhard, H.J. 1984. J. Immunol. Methods 73, 203. Cochrane, C.G., et al. 1970. J. Immunol. 105, 55. Ballows, M. and Cochrane, C.G. 1969. J. Immunol. 103, 944.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	20-December-2010 JSW
Synonyms	Cobra Venom Anticomplementary Protein
Description	Native cobra venom factor from Naja naja kaouthia. Glycoprotein composed of three nonidentical disulfide-bound subunits with M.W. of 68,000 (α), 48,000 (β), and 30,000 (γ). Cobra Venom Factor (CVF) is a structural and functional analog of cobra, as well as mammalian C3. In the presence of Factor B, Factor D, and Mg²⁺, CVF can form a stable CVF, Bb complex which is a C3/C5 convertase enzyme; however, the CVF,Bb complex is not susceptible to regulation by Factors H and I. Four to six µg of purified CVF is equal to 1.0 unit of functional activity as measured by the method of Cochrane, et al.
Form	Liquid
Formulation	In PBS, pH 7.2.
Concentration Label	Please refer to vial label for lot-specific concentration
Purity	≥95% by SDS-PAGE
Contaminants	Phospholipase: none detected
Activity	≥250 units/ml
Storage	Avoid freeze/thaw ≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).
Toxicity	Harmful
References	Bogers, W.M., et al. 1993. Eur. J. Immunol. 23, 433. Fritzinger, D.C., et al. 1992. J. Immunol. 149, 3554. Muller, B. and Muller-Ruchholtz, W. 1987. Leuk. Res. 11, 461. Vogel, C.W. and Muller-Eberhard, H.J. 1984. J. Immunol. Methods 73, 203. Cochrane, C.G., et al. 1970. J. Immunol. 105, 55. Ballows, M. and Cochrane, C.G. 1969. J. Immunol. 103, 944.

种类

Life Science Research > Proteins and Enzymes > Other Proteins

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