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	48-602MAG	Buffer Detection Kit for Magnetic Beads	1 Kit

612080 Sigma-AldrichTIMP-1, Human Neutrophil Granulocyte - Calbiochem

Native TIMP-1 from human granulocyte.

MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents.

MSDS
分析证书
参考
Data Sheet

同义词: Tissue Inhibitor of Metalloproteinase-1

Primary Target: MMP activity

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概述

Replacement Information

Description
Overview	Native TIMP-1 from human granulocyte. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stoichiometric complex with latent and active MMPs. Binds to pro-MMP-9 and MMP-9 via their C-terminal domains.
Catalogue Number	612080
Brand Family	Calbiochem®
Synonyms	Tissue Inhibitor of Metalloproteinase-1

References
References	Kolkenbrock, H., et al. 1996. Biol. Chem. 377, 529. Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.

Product Information
ATP Competitive	N
Form	Liquid
Formulation	In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ^® 35 Detergent, 0.05% NaN₃, pH 7.0.
Reversible	N
Quality Level	MQ100

Applications

Biological Information
Primary Target	MMP activity
Purity	≥90% by SDS-PAGE
Source	Prepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Concentration Label	Please refer to vial label for lot-specific concentration

Physicochemical Information
Cell permeable	N

Dimensions

Materials Information

Toxicological Information

Safety Information according to GHS

Safety Information

Product Usage Statements

Storage and Shipping Information
Ship Code	Dry Ice Only
Toxicity	Standard Handling
Storage	≤ -70°C
Avoid freeze/thaw	Avoid freeze/thaw
Do not freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).

Packaging Information

Transport Information

Supplemental Information

Specifications

Global Trade Item Number
产品目录编号	GTIN
612080	0

Documentation

TIMP-1, Human Neutrophil Granulocyte - Calbiochem MSDS

职位
物料安全数据表 (MSDS)

TIMP-1, Human Neutrophil Granulocyte - Calbiochem 分析证书

标题	批号
612080	输入批号

参考

参考信息概述
Kolkenbrock, H., et al. 1996. Biol. Chem. 377, 529. Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.

数据表

Note that this data sheet is not lot-specific and is representative of the current specifications for this product. Please consult the vial label and the certificate of analysis for information on specific lots. Also note that shipping conditions may differ from storage conditions.

Revision	23-March-2009 JSW
Synonyms	Tissue Inhibitor of Metalloproteinase-1
Description	Native TIMP-1 from human granulocyte. Member of a family of inhibitors that participate in the activation and regulation of MMP activity. Forms a non-covalent stochiometric complex with latent and active MMPs. Binds to pro-MMP-9 and MMP-9 via their C-terminal domains.
Form	Liquid
Formulation	In 200 mM NaCl, 50 mM Tris-HCl, 5 mM CaCl₂, 1 µM ZnCl₂, 0.05% BRIJ^® 35 Detergent, 0.05% NaN₃, pH 7.0.
Concentration Label	Please refer to vial label for lot-specific concentration
Source	Prepared from stimulated neutrophils that have been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.
Purity	≥90% by SDS-PAGE
Storage	Avoid freeze/thaw ≤ -70°C
Do Not Freeze	Ok to freeze
Special Instructions	Following initial thaw, aliquot and freeze (-70°C).
Toxicity	Standard Handling
References	Kolkenbrock, H., et al. 1996. Biol. Chem. 377, 529. Kolkenbrock, H., et al. 1995. Biol. Chem. Hoppe Seyler 376, 495.

种类

Life Science Research > Inhibitors and Biochemicals > Small Molecules & Inhibitors > Proteases Inhibitors > Tissue Inhibitors of Matrix Metalloproteinases (TIMPs)

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